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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Nephrol. Dec 25, 2025; 14(4): 110268
Published online Dec 25, 2025. doi: 10.5527/wjn.v14.i4.110268
Published online Dec 25, 2025. doi: 10.5527/wjn.v14.i4.110268
Ultrasound-guided erector spinae plane block for perioperative analgesia in laparoscopic nephrectomy: A systematic review and meta-analysis
Suhaina Amir, Abdul Hannan Siddiqui, Muhammad Haris, Fatima Laique, Bushra Amini, Mariam Mehboob, Mubashir Mohiuddin, Muhammad Mazhar Azam, Sameen Mukhtar, Abdul Moeed, Department of Internal Medicine, Dow University of Health Sciences, Karachi 74200, Sindh, Pakistan
Zainab Akram, Sahar Rizwan, Department of Internal Medicine, Jinnah Sindh Medical University, Karachi 75510, Sindh, Pakistan
Bibi Zainab, Department of Internal Medicine, Mekran Medical College, Turbat, Turbat 93000, Balochistan, Pakistan
Salim Surani, Department of Medicine and Pharmacology, Texas A&M University, College Station, TX 77843, United States
Co-first authors: Suhaina Amir and Abdul Hannan Siddiqui.
Author contributions: Amir S contributed to the meta-regression and manuscript writing, including the sensitivity analysis, meta-regression, discussion, and conclusion; Siddiqui AH contributed to the overall coordination and manuscript review; Haris M and Laique F contributed to data analysis; Amini B contributed to manuscript writing (Introduction and Methods); Mehboob M contributed to manuscript writing (Results); Mohiuddin M and Azam MM contributed to data extraction; Mukhtar S contributed to quality assessment, PRISMA, and preparation of the supplementary file; Akram Z, Zainab B, and Rizwan S contributed to data collection and screening; Moeed A contributed to manuscript review and revisions; Surani S contributed to conceptual supervision, final review, and critical revision of the manuscript; all authors contributed to the development and completion of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Abdul Hannan Siddiqui, Researcher, Department of Internal Medicine, Dow University of Health Sciences, Mission Road, Karachi 74200, Sindh, Pakistan.
Received: June 4, 2025
Revised: July 16, 2025
Accepted: October 28, 2025
Published online: December 25, 2025
Processing time: 202 Days and 17.2 Hours
Revised: July 16, 2025
Accepted: October 28, 2025
Published online: December 25, 2025
Processing time: 202 Days and 17.2 Hours
Core Tip
Core Tip: Erector spinae plane block (ESPB) demonstrates significant efficacy in reducing postoperative opioid use following laparoscopic nephrectomy, highlighting its potential as a promising alternative for enhanced pain management. While ESPB shows promise in lowering patient-controlled analgesia requirements compared to traditional methods, its impact on discharge times and nausea/vomiting remains inconclusive. Future large-scale randomized controlled trials are crucial to validate these findings and explore ESPB's long-term benefits in optimizing recovery pathways for nephrectomy patients.