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World J Nephrol. Dec 25, 2025; 14(4): 109168
Published online Dec 25, 2025. doi: 10.5527/wjn.v14.i4.109168
Updates in the management of intradialytic hypotension: Emerging strategies and innovations
Intissar Haddiya, Gregorius Diel Franta Iogi Simanjuntak, Sara Ramdani
Intissar Haddiya, Department of Nephrology, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, Oujda-Angad 60049, Oriental, Morocco
Intissar Haddiya, Sara Ramdani, Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, Oujda-Angad 60049, Oriental, Morocco
Gregorius Diel Franta Iogi Simanjuntak, Faculty of Medicine, University of Riau, Pekanbaru 28133, Riau, Indonesia
Author contributions: Haddiya I designed the research study, critically revised the manuscript for intellectual content; Simanjuntak GDFI and Ramdani S did the research, analyzed the data and wrote the manuscript; all authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare that there are no commercial, personal, political, intellectual, or religious conflicts of interest related to this manuscript.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sara Ramdani, PhD, Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, Hay al Hikma, Oujda-Angad 60049, Oriental, Morocco. sara.ramdani001@gmail.com
Received: May 8, 2025
Revised: June 17, 2025
Accepted: September 17, 2025
Published online: December 25, 2025
Processing time: 229 Days and 20.3 Hours
Core Tip

Core Tip: Intradialytic hypotension remains a critical complication in haemodialysis, lacking a universal definition and significantly impacting patient morbidity and mortality. This comprehensive review elucidates the complex interplay of its pathophysiology, diverse risk factors, and severe consequences. It critically evaluates current management strategies, highlighting the limitations of existing definitions and the need for individualised approaches. The review underscores the promise of emerging technologies like artificial intelligence for prediction and the importance of multidisciplinary care and patient education. Ultimately, it advocates for a unified definition and strategically directs future research to optimize prevention and treatment, thereby improving outcomes for this vulnerable population.