Al-Haggar MS, Abdelmoneim ZA. Modified National Early Warning Score 2, warning system for predicting treatment outcomes in patients with emphysematous pyelonephritis. World J Nephrol 2025; 14(3): 107879 [DOI: 10.5527/wjn.v14.i3.107879]
Corresponding Author of This Article
Zahraa A Abdelmoneim, MD, Lecturer, Department of Pediatrics, Genetics and Metabolic Unit, Mansoura University Children’s Hospital, EL Gomhoria Street, Mansoura 35516, Egypt. hzahraa211@gmail.com
Research Domain of This Article
Critical Care Medicine
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Nephrol. Sep 25, 2025; 14(3): 107879 Published online Sep 25, 2025. doi: 10.5527/wjn.v14.i3.107879
Modified National Early Warning Score 2, warning system for predicting treatment outcomes in patients with emphysematous pyelonephritis
Mohammad S Al-Haggar, Zahraa A Abdelmoneim
Mohammad S Al-Haggar, Zahraa A Abdelmoneim, Department of Pediatrics, Genetics and Metabolic Unit, Mansoura University Children’s Hospital, Mansoura 35516, Egypt
Author contributions: Al-Haggar MS revised the manuscript; Abdelmoneim ZA wrote the manuscript.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zahraa A Abdelmoneim, MD, Lecturer, Department of Pediatrics, Genetics and Metabolic Unit, Mansoura University Children’s Hospital, EL Gomhoria Street, Mansoura 35516, Egypt. hzahraa211@gmail.com
Received: April 2, 2025 Revised: May 20, 2025 Accepted: September 2, 2025 Published online: September 25, 2025 Processing time: 168 Days and 23.1 Hours
Core Tip
Core Tip: Emphysematous pyelonephritis (EPN) is a life-threatening necrotizing infection of the upper urinary tract, predominantly affecting individuals with diabetes mellitus. Early diagnosis and severity assessment are critical due to its high mortality rate. This study proposes a modified National Early Warning Score 2 (mNEWS 2) to enhance risk stratification and predictive accuracy in EPN management. By refining physiological parameter thresholds and incorporating weighted risk indices, mNEWS 2 improves triaging, prioritizes intensive monitoring, and facilitates timely interventions. Validated through receiver operating characteristic curve analysis, the mNEWS 2 score, particularly at a cutoff of 15, maximizes predictive performance for mortality risk and intervention needs.
