Ribeiro J, Ferreira D, Arrabalde C, Almeida S, Baldaque I, Sousa H. Prevalence of adenovirus and rotavirus infection in immunocompromised patients with acute gastroenteritis in Portugal. World J Virology 2015; 4(4): 372-376 [PMID: 26568919 DOI: 10.5501/wjv.v4.i4.372]
Corresponding Author of This Article
Hugo Sousa, MD, PhD, Virology Service, Portuguese Institute of Oncology of Porto, Rua Dr. António Bernardino Almeida, 4200-072 Porto, Portugal. hugomls@gmail.com
Research Domain of This Article
Virology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Joana Ribeiro, Célia Arrabalde, Sandra Almeida, Inês Baldaque, Hugo Sousa, Virology Service, Portuguese Institute of Oncology of Porto, 4200-072 Porto, Portugal
Joana Ribeiro, Delfim Ferreira, Hugo Sousa, Molecular Oncology and Viral Pathology Group, Portuguese Institute of Oncology of Porto, 4200-072 Porto, Portugal
Joana Ribeiro, Research Department, Portuguese League Against Cancer (Liga Portuguesa Contra o Cancro - Núcleo Regional do Norte), 4200-177 Porto, Portugal
Author contributions: Almeida S and Baldaque I performed the experimental tests for Adv and RV detection; Ribeiro J, Ferreira D, and Arrabalde C were responsible for the data collection; Ribeiro J and Sousa H analyzed data; Ribeiro J and Ferreira D wrote the paper; Sousa H supervised the study; all authors have provided the final approval of the manuscript.
Conflict-of-interest statement: All authors declare no conflicts of interest with any competing financial interest for the work described in this paper.
Data sharing statement: Not applied.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Hugo Sousa, MD, PhD, Virology Service, Portuguese Institute of Oncology of Porto, Rua Dr. António Bernardino Almeida, 4200-072 Porto, Portugal. hugomls@gmail.com
Telephone: +351-22-5084000 Fax: +351-22-5084001
Received: May 8, 2015 Peer-review started: May 9, 2015 First decision: June 3, 2015 Revised: September 9, 2015 Accepted: September 29, 2015 Article in press: September 30, 2015 Published online: November 12, 2015 Processing time: 188 Days and 9.4 Hours
Core Tip
Core tip: Acute gastroenteritis has been associated with significant rates of morbidity and mortality among immunocompromised patients. Rotavirus (RV) and adenovirus (AdV) are described as common agents of viral gastroenteritis causing acute diarrhoea. This is the first study in Portugal to characterize the prevalence and seasonal features of RV and AdV infections in immunocompromised patients with acute gastroenteritis. Results revealed 12.4% AdV positive samples and 0.8% RV positive samples, which correspond to a prevalence of 6.5% and 1.5%, respectively. Our results also demonstrate the importance of to add more screening methods for other emergent enteric viruses, in order to avoid the morbidity and mortality of the immunocompromised patients.
