Systematic Reviews
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Virol. Sep 25, 2022; 11(5): 352-361
Published online Sep 25, 2022. doi: 10.5501/wjv.v11.i5.352
Mortality rate of COVID-19 infection in end stage kidney disease patients on maintenance hemodialysis: A systematic review and meta-analysis
Ivan Cancarevic, Mahmoud Nassar, Ahmed Daoud, Hatem Ali, Nso Nso, Angelica Sanchez, Avish Parikh, Asma Ul Hosna, Bhavana Devanabanda, Nazakat Ahmed, Karim M Soliman
Ivan Cancarevic, Mahmoud Nassar, Nso Nso, Avish Parikh, Asma Ul Hosna, Bhavana Devanabanda, Nazakat Ahmed, Department of Medicine, Icahn School of Medicine at Mount Sinai (NYC Health and Hospitals: Queens), New York, NY 11432, United States
Ahmed Daoud, Department of Medicine, Kasr Alainy Medical School, Cairo University, Cairo 11562, Egypt
Hatem Ali, Department of Medicine, University Hospitals Coventry and Warwickshire NHS Trust, Coventry CV2 2DX, United Kingdom
Angelica Sanchez, Department of Medicine, Universidad Autonoma de Santo Domnigo, Santo Domingo 10105, Dominican Republic
Karim M Soliman, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, United States
Author contributions: All authors shared in preparing, writing and reviewing the manuscript.
Conflict-of-interest statement: All authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Karim M Soliman, MD, MSc, Associate Professor, Department of Medicine, Medical University of South Carolina, 97 Jonathan Lucas St., Charleston, SC 29425, United States. drkarimsoliman@gmail.com
Received: February 1, 2022
Peer-review started: February 1, 2022
First decision: April 8, 2022
Revised: May 20, 2022
Accepted: July 25, 2022
Article in press: July 25, 2022
Published online: September 25, 2022
Processing time: 234 Days and 11.8 Hours
Core Tip

Core tip: This is a systematic review to find out the mortality of coronavirus disease 2019 (COVID-19) infection in end stage kidney disease patients that are on regular maintenance hemodialysis. We found that COVID-19 incidence among patients on hemodialysis was significant, over 10% in some studies. Those who developed COVID-19 infection were most likely going to be hospitalized, and over 1 in 5 died from the infection. Intensive care unit admission rate was lower than the infection lethality rate. Biochemical abnormalities and dyspnea were generally reported to be associated with adverse outcomes.