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Nov 25, 2022 (publication date) through Feb 15, 2026
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World Journal of Virology
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2220-3249
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Letter to the Editor
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Virol. Nov 25, 2022; 11(6): 496-501
Published online Nov 25, 2022. doi: 10.5501/wjv.v11.i6.496
Global challenge with the SARS-CoV-2 omicron BA.2 (B.1.1.529.2) subvariant: Should we be concerned?
Jalil Roohani, Masoud Keikha
Jalil Roohani, Department of Biotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad 13131-99137, Iran
Masoud Keikha, Department of Medical Microbiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
Author contributions: Rouhani J and Keikha M wrote and edited the draft; Keikha M contributed to the study design and data collection; and all authors read and approved the final version of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Masoud Keikha, Doctor, MD, Pediatric Gastroenterology Fellow, Department of Medical Microbiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran. masoud.keykha90@gmail.com
Received: May 19, 2022
Peer-review started: May 19, 2022
First decision: August 22, 2022
Revised: August 23, 2022
Accepted: October 4, 2022
Article in press: Octobe 4, 2022
Published online: November 25, 2022
Processing time: 182 Days and 21.3 Hours
Abstract

BA.2 is a novel omicron offshoot of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has gone viral. There is limited knowledge regarding this variant of concern. Current evidence suggests that this variant is more contagious but less severe than previous SARS-CoV-2 variants. However, there is concern regarding the virus mutations that could influence pathogenicity, transmissibility, and immune evasion.

Keywords: SARS-CoV-2; Omicron; BA.2; B.1.1.529.2; Subvariant

Core Tip: BA.2 is novel omicron offshoot that goes viral. There is limit knowledge regarding this variant of concern. Current evidence suggested this variant is more contagious but less severe than previous severe acute respiratory syndrome coronavirus 2 previous variants. However, there is concern regarding the virus mutations that could be influenced pathogenicity, transmissibility as well as immune evasion.
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