Comparative study of living donor kidney transplants: Right vs left

Table 1 Donor and recipient demographics and transplant factors

Parameters	Living donor kidneys (n = 250)
	Right kidney	Left kidney	P value
Donor age in years	35.1 ± 10.5	33.6 ± 10.1	0.36
Donor sex	Males = 28 (50), females = 28 (50)	Males = 98 (51), females = 96 (49)	0.9
Mean donor weight in kg	65.9 ± 8.8	66.2 ± 11	0.9
Mean recipient age in years	37 ± 11.6	38.7 ± 11.3	0.32
Recipient sex	Males = 49 (87), females = 7 (13)	Males = 164 (84), females = 30 (16)	0.6
Mean recipient body mass index	23.6 ± 3.5	24.4 ± 3.8	0.1
Mean human leukocyte antigen mismatches, n ± SD	5 ± 2.9	5.5 ± 2.9	0.32
Donor kidney split function	47 ± 2	50 ± 2	0.000
Donor arteries multiplicity	Single = 51 (91), multiple = 5 (9)	Single = 161 (84), multiple = 31 (16)	0.17
Donor type	LRD = 42 (75), LURD = 14 (25)	LRD = 155 (80), LURD = 39 (20)	0.43
Donor nephrectomy type	ODN = 53 (95), LDN = 3 (5)	ODN = 182 (73), LDN = 68 (27)	0.000
Immunosuppressant, steroid sparing	6 (10.7)	20 (10.3)	0.9
Mean cold ischemia time in minutes	40.1 ± 16.6	48.6 ± 23.6	0.01
Mean donor warm ischemia in minutes	2.1 ± 0.9	2.7 ± 1.7	0.008
Mean recipient warm ischemia in minutes	44.2 ± 5.2	45.3 ± 8.3	0.36
Mean donor warm ischemia of cohort in minutes	ODN = 1.8 ± 0.9, LDN = 4.7 ± 1.2		0.000
Mean cold ischemia time of cohort in minutes	ODN = 41.5 ± 18.3, LDN = 60.4 ± 26.8		0.00

Data are n (%) or mean ± standard deviation (SD), unless otherwise indicated. LDN: Laparoscopic donor nephrectomy; LRD: Living related donor; LURD: Living unrelated donor; ODN: Open donor nephrectomy.

Table 2 Transplant outcomes and post-transplant serum creatinine trends

Parameter	Right kidney	Left kidney	P value
Immediate graft function	53 (96)	192 (99)	0.15
Slow graft function	1 (1.7)	1 (0.5)
Delayed graft function	1 (1.7)	0
Technical graft loss	1 (1.7)	1 (0.5)
Mean pre-transplant SC in mg/dL	5.90 ± 2.05	5.78 ± 1.57	0.7
Mean time in hours to 50% fall in pre-transplant SC	17.36 ± 7.38	17.82 ± 10.15	0.8
Mean SC on post-transplant day 7 in mg/dL	1.107 ± 0.61	1.073 ± 0.42	0.6
Mean post-transplant time in days to normal SC	4.13 ± 2.848	4.11 ± 2.774	0.9
Mean SC on last follow-up in mg/dL	1.033 ± 0.217	1.038 ± 0.443	0.9

Data are n (%). SC: Serum creatinine.

Table 3 Cohort post-transplant serum creatinine trend

Parameter	Frequency		SC to decrease by 50% in hours	P value	Normalize SC	P value	SC at last follow-up	P value	SC on day 7 after surgery in days	P value
Open donor nephrectomy	RK	53 (95)	17.9 ± 10.2	0.6	4 ± 2.7	0.4	0.9 ± 0.2	0.02	1 ± 0.5	0.9
	LK	129 (67)
	Total	182 (73)
Laparoscopic donor nephrectomy	RK	3 (5)	17.2 ± 7.5		4.4 ± 2.8		1.1 ± 0.6		1 ± 0.3
	LK	65 (33)
	Total	68 (27)
Living related donor	RK	42 (75)	17.3 ± 10	0.2	4 ± 2.7	0.2	0.99	0.000	1.0 ± 0.4	0.005
	LK	155 (80)
	Total	197 (79)
Living unrelated donor	RK	14 (25)	19.1 ± 7		4.6 ± 2.9		1.2		1.2 ± 0.8
	LK	39 (20)
	Total	53 (21)
Steroid sparing immunosuppression	RK	6 (11)	15 ± 0.7	0.13	3.5 ± 2.4	0.23	0.97 ± 0.2	0.36	0.9 ± 0.4	0.07
	LK	20 (10)
	Total	26 (10)
Steroid based immunosuppression	RK	50 (89)	18 ± 0.9		4.2 ± 2.8		1 ± 0.4		1.1 ± 0.5
	LK	174 (90)
	Total	224 (90)

Data are n (%).LK: Left kidney; RK: Right kidney; SC: Serum creatinine.