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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Mar 18, 2026; 16(1): 110628
Published online Mar 18, 2026. doi: 10.5500/wjt.v16.i1.110628
Published online Mar 18, 2026. doi: 10.5500/wjt.v16.i1.110628
Silent cardiac burden: Echocardiographic abnormalities and their predictors in kidney transplant candidates and their impact on graft function
Nihal Mohammed Sadagah, Muhammad Abdul Mabood Khalil, Hinda Hassan Khideer Mahmood, Salem H Al-Qurashi, Center of Renal Diseases and Transplantation, King Fahad Armed Forces Hospital Jeddah, Jeddah 23311, Saudi Arabia
Ibtisam Ali Alghamdi, Ghada Abdulrahman Buridi, Department of Medicine, King Fahad Armed Forces Hospital, Jeddah 23311, Makkah al Mukarramah, Saudi Arabia
Author contributions: Al-Qurashi SH, Khalil MAM, and Sadagah NM conceived the study idea; Khalil MAM drafted the initial draft, and all authors (Sadagah NM, Khalil MAM, Mahmood HHK, Alghamdi IA, Buridi GA, and Al-Qurashi SH) critically reviewed the draft; Khalil MAM revised and all authors approved the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of our institution.
Informed consent statement: Informed consent was obtained from all participants or their legally authorized representatives.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement- checklist of items.
Data sharing statement: Data will be made available upon reasonable request and approval by the Institutional Research Ethics Review Committee.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Muhammad Abdul Mabood Khalil, FRCP, Center of Renal Diseases and Transplantation, King Fahad Armed Forces Hospital Jeddah, Al Kurnaysh Br Road, Al Andalus, Jeddah 23311, Saudi Arabia. doctorkhalil1975@hotmail.com
Received: June 24, 2025
Revised: July 30, 2025
Accepted: November 11, 2025
Published online: March 18, 2026
Processing time: 208 Days and 12.7 Hours
Revised: July 30, 2025
Accepted: November 11, 2025
Published online: March 18, 2026
Processing time: 208 Days and 12.7 Hours
Core Tip
Core Tip: Despite clearance by a cardiologist, kidney transplant recipients have structural and functional abnormalities. These abnormalities may partially resolve after transplantation, but not wholly. Abnormalities such as left ventricular hypertrophy, left ventricular systolic dysfunction, diastolic dysfunction, pulmonary hypertension may have an impact on graft and patient survival. Understanding their predictors may help alleviate these abnormalities and improve patient and graft survival. This will enable clinicians to devise a pathway to reduce cardiovascular events, improve long-term graft function, and decrease mortality.