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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Mar 18, 2026; 16(1): 110485
Published online Mar 18, 2026. doi: 10.5500/wjt.v16.i1.110485
Published online Mar 18, 2026. doi: 10.5500/wjt.v16.i1.110485
ChatGPT in liver transplantation: Current applications, limitations, and future directions
Eleni Avramidou, Stella Vasileiadou, Georgios Katsanos, Georgios Tsoulfas, Department of Transplantation Surgery, Center for Research and Innovation in Solid Organ Transplantation, Aristotle University of Thessaloniki, Thessaloniki 54642, Greece
Nikolaos Kougianos, George Chiotis-Miehe, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki 54642, Greece
Author contributions: Avramidou E conceptualized the idea, visualized, collected, analyzed the data, and wrote the manuscript; Kougianos N collected and analyzed the data; and wrote the manuscript; Chiotis-Miehe G collected and analyzed the data, and wrote the manuscript; Vasileiadou S critically reviewed the manuscript; Katsanos G critically reviewed the manuscript; Tsoulfas G supervised, assisted with the data curation, and edited the manuscript; and all authors have read and agreed to the published version of the manuscript.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Eleni Avramidou, MD, Department of Transplantation Surgery, Center for Research and Innovation in Solid Organ Transplantation, Aristotle University of Thessalo
Received: June 9, 2025
Revised: August 13, 2025
Accepted: December 17, 2025
Published online: March 18, 2026
Processing time: 221 Days and 14.9 Hours
Revised: August 13, 2025
Accepted: December 17, 2025
Published online: March 18, 2026
Processing time: 221 Days and 14.9 Hours
Core Tip
Core Tip: ChatGPT is an advanced artificial intelligence tool that recently has an expanding role in the field of medicine. Particularly, in the field of liver transplantation (LT) it offers promising applications in clinical, research and educational fields. Current applications include documentation, organ allocation assistance and patient education. Despite future applications suggesting expanding usage of this tool in LT, limitations in data accuracy and ethical concerns remain, with establishment of structured guidelines being essential. This minireview presents the current literature regarding applications of ChatGPT in LT as well as its limitations and future applications.