Retrospective Cohort Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Jun 18, 2024; 14(2): 91081
Published online Jun 18, 2024. doi: 10.5500/wjt.v14.i2.91081
Safety and efficacy of Kaffes intraductal self-expanding metal stents in the management of post-liver transplant anastomotic strictures
Chee Lim, Jonathan Ng, Babak Sarraf, Rhys Vaughan, Marios Efthymiou, Leonardo Zorron Cheng Tao Pu, Sujievvan Chandran
Chee Lim, Jonathan Ng, Babak Sarraf, Rhys Vaughan, Marios Efthymiou, Leonardo Zorron Cheng Tao Pu, Sujievvan Chandran, Department of Gastroenterology and Hepatology, Austin Health, Melbourne Heidelberg, VIC 3084, Australia
Rhys Vaughan, Marios Efthymiou, Leonardo Zorron Cheng Tao Pu, Sujievvan Chandran, Melbourne Medical School, The University of Melbourne, Melbourne Parkville, VIC 3052, Australia
Author contributions: Chandran S, Efthymiou M and Vaughan R formulated the research question; Chandran S designed the study; Lim C, Ng J and Sarraf B conducted the research; Lim C and Zorron Cheng Tao Pu L analyzed and interpreted the data; Lim C and Zorron Cheng Tao Pu L wrote the manuscript. All authors have read and approve the final manuscript.
Institutional review board statement: The project has been reviewed by Austin Health Office for Research against the principles of the National Statement on Ethical Conduct in Research (2007, updated 2018) and approved. (Approval Number: Audit/22/Austin/43).
Informed consent statement: This is an informed consent exemption statement. This application is a clinical audit project involving the collection, use and disclosure of the data in a de-identified format to be conducted at Austin Health. Such data is to be accessed by an Austin Health employee only.
Conflict-of-interest statement: All authors have nothing to disclose.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at leonardo.zorronchengtaopu@austin.org.au. Presented data was de-identified and anonymised, and risk of identification is low.
STROBE statement: The authors have read the STROBE statement-checklist of items, and the manuscript was prepared and revised according to the STROBE statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Leonardo Zorron Cheng Tao Pu, MD, MSc, PhD, Doctor, Staff Physician, Department of Gastroenterology and Hepatology, Austin Health, 145 Studley Road 8th floor, Harold Stokes Building, Advanced Endoscopy Unit, Melbourne Heidelberg, VIC 3084, Australia. leozorron@gmail.com
Received: December 21, 2023
Revised: March 8, 2024
Accepted: March 25, 2024
Published online: June 18, 2024
Processing time: 175 Days and 22.5 Hours
Core Tip

Core Tip: Biliary strictures are the most common complication post orthotopic liver transplantation. This retrospective study evaluates the safety and efficacy of managing such strictures using intraductal fully-covered metal stent (Kaffes) for different durations. The results show that a single Kaffes stent indwelling for at least 4 months is safe and effective for treating post liver transplant anastomotic strictures.