Systematic Reviews
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Mar 18, 2025; 15(1): 96870
Published online Mar 18, 2025. doi: 10.5500/wjt.v15.i1.96870
Literature study on traditional Chinese medicine syndromes after renal transplantation
Yun-Peng Guo, Ling-Xue Bao, Yu-Yang Wang, Quan Wen, Gai Hang, Bo Chen
Yun-Peng Guo, Yu-Yang Wang, Tongliao Clinical Medical College, Inner Mongolia Medical University, Tongliao 028000, Inner Mongolia Autonomous Region, China
Ling-Xue Bao, Quan Wen, Gai Hang, Bo Chen, Department of Urology, Tongliao People's Hospital, Tongliao 028000, Inner Mongolia Autonomous Region, China
Author contributions: Guo YP was responsible for drafting of manuscript; Bao LX and Wen Q were responsible for data acquisition; Wang YY and Hang G were responsible for data analysis; Chen B was responsible for study concept, design and critical revision of the manuscript; all authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare that they have no competing interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bo Chen, Doctor, MD, PhD, Chief Doctor, Director, Department of Urology, Tongliao People's Hospital, No. 668 Horqin Street, Horqin District, Tongliao 028000, Inner Mongolia Autonomous Region, China. chenmuxin@126.com
Received: May 17, 2024
Revised: October 2, 2024
Accepted: November 12, 2024
Published online: March 18, 2025
Processing time: 193 Days and 23.6 Hours
Abstract
BACKGROUND

Kidney transplantation is the most effective means to treat patients with renal failure, but its postoperative problems such as rejection reactions, immunosuppressant poisoning, chronic transplant kidney nephropathy, etc. still have not been effectively solved. This study searched for literature on traditional Chinese medicine (TCM) syndromes after kidney transplantation in China, conducted statistical analysis of the results, and sought to identify the underlying patterns.

AIM

To understand the TCM syndromes after renal transplantation and associated rules and provide a theoretical basis for further clinical research.

METHODS

The literature pertaining to TCM syndromes in renal transplantation, published in the China National Knowledge Infrastructure, Wanfang database, and WIP database from 1970 to 2021, was meticulously searched and comprehensively and statistically analyzed.

RESULTS

Following the established inclusion and exclusion criteria, 13 studies were selected for analysis. Post-renal transplantation, no significant discrepancy was noted among the groups based on the location of TCM viscera. However, when categorized according to TCM pathogenic factors, the groups with spleen and kidney yang deficiency, as well as liver and kidney yin deficiency, exhibited a statistically significant difference in the frequency.

CONCLUSION

Currently, the research on TCM syndromes pertaining to renal transplantation is in its nascent phase. It is imperative to conduct a multicentric, large-scale survey of TCM syndromes subsequent to renal transplantation in the ensuing years.

Keywords: Kidney transplantation; Syndrome; Literature analysis; Traditional Chinese medicine; Systematic review

Core Tip: At present, there are no reports on clinical research on the traditional Chinese medicine (TCM) syndromes and constitution of kidney transplant patients with multicenter and diverse approaches. This study searched for literature on TCM syndromes after kidney transplantation in China, conducted statistical analysis of the results, and sought to identify the underlying patterns.