Related factors associated with the occurrence of depressive disorders in children with asthma

Table 1 Univariate analysis of basic information of the two groups of children, n (%)/mean ± SD

Factor		Non-depression group (n = 60)	Group with depression (n = 60)	t value	P value
Age		9.35 ± 0.633	9.58 ± 0.70	1.921	0.057
Course of disease		2.34 ± 0.42	2.40 ± 0.35	0.708	0.480
Gender	Male	35 (58.33)	32 (53.33)	0.304	0.581
	Female	25 (41.67)	28 (46.67)
Place of residence	Urban area	32 (53.33)	29 (48.33)	0.635	0.782
	County seat	16 (26.67)	20 (33.33)
	Rural areas	12 (20.00)	11 (18.33)
Only children	Yes	24 (40.00)	26 (43.33)	0.137	0.711
	No	36 (60.00)	34 (56.67)
Education level of primary caregivers	High school and below	20 (33.33)	32 (53.33)	4.887	0.027
	College degree or above	40 (66.67)	28 (46.66)
Negative emotions of primary caregivers	Have	23 (38.33)	36 (60.00)	5.635	0.018
	None	37 (61.67)	24 (40.00)
Family history of asthma	Yes	23 (38.33)	35 (58.33)	4.805	0.028
	No	37 (61.67)	25 (41.67)
Parents’ level of understanding of asthma	Better	41 (68.33)	27 (45.00)	6.652	0.010
	Poor	19 (31.67)	33 (55.00)
Medication use guidelines	Better	40 (66.67)	29 (48.33)	4.126	0.042
	Poor	20 (33.33)	31 (51.67)
Asthma control	Better	37 (61.67)	24 (40.00)	5.635	0.018
	Poor	23 (38.33)	36 (60.00)

Table 2 Variable assignment information

Factor	Assignment
Depression in children with asthma	No depression group = 0; with depression group = 1
Education level of primary caregivers	College degree or above = 0; high school diploma or below = 1
Negative emotions of primary caregivers	No = 0; yes = 1
Family history of asthma	No = 0; yes = 1
Parents’ level of understanding of asthma	Better = 0; poor = 1
Medication use guidelines	Better = 0; poor = 1
Asthma control	Better = 0; poor = 1

Table 3 Logistic regression analysis of asthmatic children with comorbid depression

Factor	β	SE	Wald χ²	P value	Odds ratio (95%CI)
Education level of primary caregivers	0.926	0.447	4.294	0.038	2.523 (1.051-6.055)
Negative emotions of primary caregivers	1.351	0.465	8.437	0.004	3.826 (1.552-9.612)
Family history of asthma	0.966	0.444	4.734	0.030	2.628 (1.101-6.273)
Parents’ level of understanding of asthma	1.332	0.470	8.017	0.005	3.787 (1.507-9.520)
Medication use guidelines	1.067	0.454	5.520	0.019	2.908 (1.194-7.083)
Asthma control	1.386	0.455	9.260	0.002	3.997 (1.637-9.758)

Table 4 Receiver operating characteristic analysis of asthmatic children with comorbid depression

Factor	Area under the curve	Specificity	Sensitivity	Youden index	95%CI	P value
Education level of primary caregivers	0.600	66.67	53.33	0.200	0.507-0.688	0.025
Negative emotions of primary caregivers	0.608	61.67	60.00	0.217	0.515-0.696	0.015
Family history of asthma	0.600	61.67	58.33	0.200	0.513-0.720	0.026
Parents’ level of understanding of asthma	0.617	68.33	55.00	0.233	0.524-0.704	0.008
Medication use guidelines	0.592	66.67	51.67	0.183	0.498-0.680	0.040
Asthma control	0.625	61.67	63.33	0.250	0.532-0.712	0.005