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World J Psychiatry. Jul 19, 2026; 16(7): 118608
Published online Jul 19, 2026. doi: 10.5498/wjp.118608
Published online Jul 19, 2026. doi: 10.5498/wjp.118608
Related factors associated with the occurrence of depressive disorders in children with asthma
Hai-Xia Li, You-Jun Zhou, Min Zhou, Chuang Chen, Yi Chang, Ya-Lu Wang, Department of Traditional Chinese Medicine, The Affiliated Children’s Hospital of Xiangya School of Medicine, Central South University (Hunan Children’s Hospital), Changsha 410007, Hunan Province, China
Author contributions: Li HX was responsible for research design, data analysis, review and editing, communication and coordination, ethical review, copyright and licensing and follow-up; Zhou YJ and Zhou M participated in research design, data collection, data analysis and paper writing; Chen C was responsible for research design and data collection; Chang Y was responsible for data analysis; Wang YL was responsible for fund application, review and editing; all authors have read and accepted the final manuscript.
Supported by National Integrated Traditional Chinese and Western Medicine “Flagship” Department Construction Project, No. 335; the Major Project of Health Science Research of Hunan Province, No. 20255835; the Joint Project of Medical and Health Industry of Hunan Provincial Natural Science Foundation, No. 2025JJ80627; and the Chronic Disease Management Research Project of National Health Commission Capacity Building and Continuing Education Center, No. GWJJMB202510023056.
Institutional review board statement: The research was reviewed and approved by the Ethics Committee of Hunan Children’s Hospital, No. KY2025-68.
Informed consent statement: All participants provided informed consent.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
STROBE statement: The authors have read the STROBE Statement – checklist of items, and the manuscript was prepared and revised according to the STROBE Statement – checklist of items.
Data sharing statement: No other data available.
Corresponding author: Hai-Xia Li, Associate Chief Pharmacist, Department of Traditional Chinese Medicine, The Affiliated Children’s Hospital of Xiangya School of Medicine, Central South University (Hunan Children’s Hospital), No. 86 Ziyuan Road, Changsha 410007, Hunan Province, China. lihaixia2012@126.com
Received: January 30, 2026
Revised: February 24, 2026
Accepted: March 27, 2026
Published online: July 19, 2026
Processing time: 146 Days and 10.2 Hours
Revised: February 24, 2026
Accepted: March 27, 2026
Published online: July 19, 2026
Processing time: 146 Days and 10.2 Hours
Core Tip
Core Tip: This analysis identifies key factors associated with depression in children with asthma, including primary caregivers’ lower education level and negative emotions, poor parental asthma knowledge, medication non-adherence, poor asthma control, and a family history of asthma. While these factors show moderate predictive value individually, they serve as crucial clinical warning signals. Recognizing these multifaceted risks enables early screening and targeted psychological interventions for at-risk children and their families, ultimately improving comprehensive asthma management and pediatric mental health outcomes.