BPG is committed to discovery and dissemination of knowledge
Retrospective Cohort Study
Copyright: ©Author(s) 2026.
World J Psychiatry. Jul 19, 2026; 16(7): 117775
Published online Jul 19, 2026. doi: 10.5498/wjp.117775
Table 1 Comparison of general data of the two groups of patients (n = 78), n (%)/mean ± SD
Index
Control group (n = 78)
Study group (n = 78)
t/χ² value
P value
Age (year)62.35 ± 5.1261.87 ± 4.980.5870.557
Gender0.1640.686
    Male44 (56.40)45 (57.69)
    Female34 (43.60)33 (42.31)
Pressure ulcer stage0.3210.571
    Phase III48 (61.54)51 (65.38)
    Phase IV 30 (38.46)27 (34.62)
Reasons for bed rest1.2350.540
    Sequelae of stroke35 (44.87)33 (42.31)
    Parkinson’s disease18 (23.08)20 (25.64)
    Alzheimer’s disease18 (23.08)16 (20.51)
    Other7 (8.97)9 (11.54)
Underlying diseases0.8760.645
    Hypertension53 (67.95)55 (70.51)
    Diabetes35 (44.87)34 (43.59)
    Coronary heart disease25 (32.05)27 (34.62)
Degree of infection0.5120.774
    Mild infection (WBC 10-15 × 109/L)30 (38.46)31 (39.74)
    Moderate infection (WBC 15-20 × 109/L)33 (42.31)32 (41.03)
    Severe infection (WBC > 20 × 109/L)16 (20.51)15 (19.23)
Table 2 Comparison of prognostic indicators between the two groups (n = 78), n (%)/mean ± SD
Index
Control group (n = 78)
Study group (n = 78)
Statistic
P value
Wound healing effectu = 2.3570.018
Recovery from illness22 (28.21)35 (44.87)
Conspicuous effect25 (32.05)24 (30.77)
Effective12 (15.38)13 (16.67)
Void of effect19 (24.36)6 (7.69)
Total effective rate (%)75.6492.31χ2 = 8.0500.005
Wound healing time (day)52.36 ± 7.8243.15 ± 6.54t = 7.981< 0.001
Total length of stay (day)58.24 ± 8.1549.37 ± 7.26t = 7.176< 0.001
Table 3 Comparison of infection and nutritional indicators between the two groups before and after intervention, n (%)/mean ± SD
Index
Time point
Control group (n = 78)
Study group (n = 78)
t/χ² value
P value
WBC (× 109/L)Before intervention16.87 ± 3.2517.02 ± 3.18-0.2910.771
After 8 weeks of intervention11.23 ± 2.158.56 ± 1.878.275< 0.001
RBC (× 1012/L)Before intervention3.52 ± 0.483.48 ± 0.510.5650.573
After 8 weeks of intervention4.01 ± 0.534.58 ± 0.49-7.245< 0.001
HBG (g/L)Before intervention102.35 ± 12.68101.87 ± 13.020.2380.812
After 8 weeks of intervention115.62 ± 11.85128.43 ± 10.96-7.246< 0.001
ALB (g/L)Before intervention32.15 ± 3.5631.87 ± 3.420.5130.609
After 8 weeks of intervention35.82 ± 3.1839.65 ± 2.87-8.092< 0.001
CRP-C (mg/L)Before intervention45.62 ± 8.7546.13 ± 8.52-0.3670.714
After 8 weeks of intervention28.35 ± 7.1216.87 ± 6.3510.732< 0.001
Positive microbial cultureBefore intervention92 (92.00)93 (93.00)0.0180.894
After 8 weeks of intervention45 (45.00)22 (22.00)11.8740.001
Table 4 Comparison of Visual Analogue Scale score, Braden score and Self-Rating Anxiety Scale score between the two groups before and after intervention, mean ± SD
Index
Time point
Control group (n = 78)
Study group (n = 78)
t value between groups
P value
VAS scoreBefore intervention7.82 ± 1.257.76 ± 1.310.2930.770
After 4 weeks of intervention5.23 ± 1.083.15 ± 0.9612.714< 0.001
After 8 weeks of intervention3.18 ± 0.871.56 ± 0.7212.666< 0.001
Braden scoreBefore intervention12.35 ± 1.8712.28 ± 1.930.2300.818
After 4 weeks of intervention14.52 ± 1.6516.87 ± 1.52-9.256< 0.001
After 8 weeks of intervention16.23 ± 1.4818.56 ± 1.37-10.206< 0.001
SAS scoreBefore intervention65.32 ± 7.8564.87 ± 8.020.3540.724
After 4 weeks of intervention52.15 ± 6.9340.23 ± 6.1511.364< 0.001
After 8 weeks of intervention45.68 ± 6.3235.12 ± 5.8710.816< 0.001
Table 5 Comparison of adverse reactions and complications between the two groups, n (%)
Indicators
Control group (n = 78)
Study group (n = 78)
χ2 value
P value
Adverse reactions0.0001.000
VSD dressing allergy3 (3.85)2 (2.56)
Adverse drug reactions (nausea, dizziness)3 (3.85)2 (2.56)
Overall incidence6 (7.69)5 (6.41)
Complications5.1000.024
Bleeding from wounds2 (2.56)1 (1.28)
The wound infection was aggravated5 (6.41)1 (1.28)
Recurrence of pressure ulcers4 (5.13)2 (2.26)
Pulmonary infection6 (7.69)2 (2.56)
Overall incidence17 (21.79)6 (7.69)


Write to the Help Desk