Study on the correlation between fatigue, anxiety, and depression in patients with chronic heart failure

Table 1 Univariate analysis of fatigue in chronic heart failure patients, n (%)

Basic information	Number of people	MFI-20 (points)	t/F value	P value
Age			1.791	0.075
< 60 years	49 (30.25)	68.89 ± 7.27
≥ 60 years	113 (69.75)	71.57 ± 9.31
Gender			0.189	0.849
Male	94 (58.02)	70.65 ± 8.34
Female	68 (41.98)	70.91 ± 8.95
Educational level			0.104	0.901
Junior high school or below	86 (53.09)	71.04 ± 9.42
Secondary specialized or high school	49 (30.25)	70.57 ± 8.66
College or above	27 (16.66)	70.21 ± 7.82
Place of residence			1.536	0.127
Urban	82 (50.62)	69.73 ± 8.26
Rural	80 (49.38)	71.82 ± 9.05
Monthly household income (RMB)			1.640	0.103
≥ 8000	71 (43.83)	69.45 ± 8.27
< 8000	91 (56.17)	71.78 ± 9.48
Comorbidity			5.128	< 0.001
Have	122 (75.31)	72.94 ± 9.97
No have	40 (24.69)	64.11 ± 7.62
NYHA functional class			4.546	< 0.001
Level I-II	49 (30.25)	66.16 ± 5.20
Level III-IV	113 (69.75)	72.75 ± 9.54
Course of heart failure			2.406	0.094
< 3 years	52 (32.10)	68.75 ± 7.35
3-5 years	79 (48.77)	71.33 ± 8.64
> 5 years	31 (19.13)	72.68 ± 9.98
Sleep quality			15.240	< 0.001
Good	36 (22.22)	64.26 ± 5.87
General	85 (52.47)	71.72 ± 8.71
Poor	41 (25.31)	74.48 ± 9.65

MFI-20: Multidimensional Fatigue Scale score; NYHA: New York Heart Association.

Table 2 Explanation of variable assignment

Variable	Data type	Description of valuation
Complication	Categorical data	0 = no have; 1 = have
NYHA cardiac function classification	Categorical data	0 = level I-II; 1 = level III-IV
Sleep state	Categorical data	0 = good; 1 = general; 2 = poor
Anxiety score	Continuous variable data	Enter actual value
Depression score	Continuous variable data	Enter actual value

NYHA: New York Heart Association.

Table 3 Multivariate regression analysis of fatigue in chronic heart failure patients

Factor	Β (95%CI)	SE	Beta	t value	P value
Complication	0.903 (0.258-1.695)	0.243	0.427	4.578	< 0.001
NYHA cardiac function grade III-IV	0.319 (0.269-0.743)	0.117	0.401	4.054	0.002
Sleep state
General	0.143 (-0.169-0.459)	0.139	0.574	1.862	0.096
Poor	0.465 (0.294-0.948)	0.147	0.665	5.691	< 0.001
Anxiety	1.728 (0.693-3.642)	0.382	0.239	5.843	< 0.001
Depressed	1.649 (0.712-3.517)	0.353	0.216	5.478	< 0.001

Note: In multiple regression analysis, variables with assignment = 0 are used as controls (dummy argument). CI: Confidence interval; NYHA: New York Heart Association.