Investigation of depressive symptoms after thyroid cancer surgery: Logistic regression analysis and adjustment strategy

Table 1 Univariate analysis of the factors affecting postoperative depression in thyroid cancer, n (%)

Correlative factor	No. of cases	Non-depressed group (n = 46)	Depressed group (n = 62)	χ2	P value
Sex
Male	46	18 (39.13)	28 (45.16)	0.393	0.531
Female	62	28 (60.87)	34 (54.84)
Age (years)
≥ 60	60	20 (43.48)	40 (64.52)	4.734	0.030
< 60	48	26 (56.52)	22 (35.48)
Domicile
Rural area	63	30 (65.22)	33 (53.23)	1.562	0.211
Town	45	16 (34.78)	29 (46.77)
Matrimonial res
Married	87	41 (89.13)	46 (74.19)	5.320	0.070
Unmarried	7	3 (6.52)	4 (6.45)
Divorced	14	2 (4.35)	12 (19.36)
Educational background
Below high school	59	19 (41.30)	40 (64.52)	5.740	0.017
High school or above	49	27 (58.70)	22 (35.48)
Per capita monthly Household income (yuan)
< 3000	52	12 (26.08)	40 (64.52)	23.152	< 0.001
3000-5000	36	17 (36.96)	19 (30.65)
> 5000	20	17 (36.96)	3 (4.83)
Family history of cancer
Yes	21	5 (10.87)	16 (25.81)	3.761	0.052
No	87	41 (89.13)	46 (74.19)
Type of tumor
Papillary carcinoma	83	38 (82.61)	45 (72.58)	1.493	0.222
Carcinoma of the follicle	25	8 (17.39)	17 (27.42)
Modus operandi
Total thyroidectomy	73	33 (71.74)	40 (64.52)	0.629	0.428
Partial thyroidectomy	35	13 (28.26)	22 (35.48)
131I treatment
Yes	40	8 (17.39)	32 (51.61)	13.262	< 0.001
No	68	38 (82.61)	30 (48.39)
Coping style
Face	66	40 (86.96)	26 (41.94)	22.522	< 0.001
Avoidance	42	6 (13.04)	36 (58.06)
Social support
Yes	70	38 (82.61)	32 (51.61)	11.125	0.001
No	38	8 (17.39)	30 (48.39)

Table 2 Factors affecting depression after surgery for thyroid cancer

Variable name	Influencing factor	Variable assignment
X1	Age (years)	< 60 = 0, ≥ 60 = 1
X2	Record of formal schooling	High school and above = 0, high school below = 1
X3	Per capita monthly household income (yuan)	> 5000 = 0, 3000-5000 = 1, < 3000 = 2
X4	131I treatment	No = 0, yes = 1
X5	Coping style	Facing = 0, avoidance/surrender = 1
X6	Social support	No = 0, yes = 1
Y	Depression symptoms	No = 0, yes = 1

Table 3 Multivariate analysis of factors affecting postoperative depression in patients with thyroid cancer

Factor	β	SE	Wald χ2	P value	OR	95%CI
Age > 60 years	1.280	0.658	3.784	0.052	3.597	0.990-13.062
Less than high school education	1.332	0.721	3.413	0.065	3.789	0.922-15.567
Per capita monthly income of the family is less than 3000 yuan	1.660	0.521	10.152	0.001	5.259	1.894-14.602
131I treatment	1.740	0.558	9.724	0.002	5.697	1.909-17.008
Avoidance/submission	1.563	0.588	7.066	0.008	4.773	1.508-15.112
social support	-1.508	0.450	11.230	0.001	0.221	0.092-0.535