Erythrocyte membrane nervonic acid in drug-naive first-episode psychosis and chronic medicated schizophrenia: Implication for impaired myelination and prognosis

Table 1 Demographic and clinical characteristics of first-episode psychosis and chronic schizophrenia patients, mean ± SD

Characteristics	CNT	FEP	CSZ
Age (year)	25 ± 7.6	23.54 ± 4.65	42.23 ± 5.12
Gender (male:female)	14:0	21:0	20:0
Age at onset of psychosis	-	22.30 ± 4.48	23.15 ± 6.55
Years of illness	-	≤ 5.0 days	22.77 ± 7.21
Total BPRS total	-	45.18 ± 12.53	38.17 ± 6.96
Total PANSS-PSS	-	21.03 ± 4.81	12.88 ± 4.10
Total PANSS-NSS	-	20.91 ± 5.10	07.82 ± 2.31
Plasma leptin (ng/mL)	5.56 ± 0.78	4.28 ± 1.42	08.33 ± 1.42
BMI (kg/m2)	25.1 ± 2.10	23.3 ± 2.22	29.66 ± 3.73
Smoking	-	2/21	3/20
Antipsychotic use	-	-	+++
Tobacco	-	-	-
Cannabis	-	-	-

CNT: Control subjects; FEP: First-episode psychosis; CSZ: Chronic schizophrenia; BPRS: Brief Psychiatric Rating Scale; PANSS-PSS: Positive and negative syndrome scale-positive symptom scores; PANSS-NSS: Positive and negative syndrome scale-negative symptom scores; BMI: Body mass index; +++: Treated with various antipsychiotic drugs.