Social function scores and influencing factors in patients with residual depressive symptoms

Table 1 Sheehan Disability Scale scores subgroups of patients with residual depressive symptoms

Data	Cases	SDS score (mean ± SD)	Z/t	P value
Sex			-0.537	0.591
Male	56	11.27 ± 3.37
Female	102	11.53 ± 3.33
Degree of depression			0.575	0.750
Mild	45	11.42 ± 3.86
Moderate	110	11.54 ± 3.07
Severe	3	13.00 ± 2.16
Disease history			-4.432	< 0.001
First-episode	67	10.03 ± 3.08
Recurrence	91	12.49 ± 2.88
Family history of depression			0.6901	0.491
Yes	33	11.15 ± 2.78
No	125	11.61 ± 3.39
Family history of depression			-0.719	0.472
1	13	12.08 ± 2.53
≥ 2	145	11.49 ± 3.37
Use of antipsychotics			-1.3891	0.167
Yes	31	12.23 ± 2.85
No	127	11.23 ± 3.26
Use of sedative and hypnotic drugs			-1.121	0.262
Yes	6	13.00 ± 2.45
No	152	11.54 ± 3.20
Medication compliance			-5.191	< 0.001
Stick to medication	140	10.77 ± 2.81
Intermittent medication use	18	15.50 ± 2.36
Therapy method			-7.546	< 0.001
Drug therapy alone	56	14.02 ± 2.66
Drugs and nursing intervention	102	9.79 ± 2.60
Comorbidities			-0.6371	0.525
Yes	19	11.95 ± 3.35
No	139	11.50 ± 3.38
Degree of somatic symptoms			48.032	< 0.001
None	48	9.35 ± 2.71
Mild	36	11.97 ± 3.39
Moderate	49	12.08 ± 2.83
Severe	25	13.80 ± 2.24
Residual symptoms			-5.710	< 0.001
Slight	107	10.46 ± 3.37
Obvious	51	13.51 ± 2.46
Age			-0.584	0.559
< 40 years	70	11.56 ± 3.24
≥ 40 years	88	11.36 ± 3.38
Years of education			-0.072	0.943
< 12 years	80	11.36 ± 3.25
≥ 12 years	78	11.56 ± 3.37
Duration from illness onset to hospital visit			-0.300	0.943
< 3 years	26	11.62 ± 3.05
≥ 3 years	132	11.39 ± 3.31
Duration of depressive episode			-1.149	0.251
< 16 weeks	80	10.83 ± 3.00
≥ 16 weeks	78	11.91 ± 3.41
SSRS score			-0.219	0.827
< 28	68	11.60 ± 3.59
≥ 28	90	11.20 ± 3.00
LES score			-1.429	0.153
< 42	78	11.80 ± 3.21
≥ 42	80	11.14 ± 3.34
FAD score			-1.735	0.083
< 138	78	10.97 ± 3.35
≥ 138	80	11.94 ± 3.20
Anxiety score			-2.353	0.019
< 8	74	10.86 ± 2.77
≥ 8	84	11.86 ± 3.57
Stigma at discharge score			-1.0181	0.310
< 75	65	11.18 ± 3.19
≥ 75	93	11.51 ± 3.90

¹Indicates that the value is statistically significant with the independent-sample t-test.

SDS: Sheehan Disability Scale; SSRS: Social Support Rating Scale; LES: Life Event Scale; FAD: Family Assessment Device.

Table 2 Correlation between significant indicators and Sheehan Disability Scale scores in patients with residual depressive symptoms

Indexes	Assignment	Correlation with SDS score
		r value	P value
Disease history	0 = first-episode; 1 = recurrence	0.354	< 0.001
Medication compliance	0 = stick to medication; 1 = intermittent medication use	0.414	< 0.001
Therapy method	0 = drug therapy alone; 1 = drugs and nursing intervention	0.602	< 0.001
Degree of somatic symptoms	0 = none; 1 = mild; 2 = moderate; 3 = severe	0.200	0.012
Residual symptoms	0 = slight; 1 = obvious	0.456	< 0.001
Anxiety score	Actual value	0.270	0.001

SDS: Sheehan Disability Scale.

Table 3 Multiple linear regression analysis of Sheehan Disability Scale scores in patients with residual depressive symptoms

Variable	β	SE	β′	t value	P value
Constant	6.908	0.756	-	9.140	< 0.001
Disease history	1.337	0.393	0.204	3.405	0.001
Medication compliance	2.748	0.594	0.269	4.624	< 0.001
Therapy method	2.237	0.431	0.330	5.195	< 0.001
Degree of somatic symptoms	0.364	0.172	0.120	2.113	0.036
Residual symptoms	1.505	0.419	0.217	3.594	< 0.001
Anxiety score	0.230	0.093	0.142	2.480	0.014

β: Non-standardized coefficient; β’: Standard coefficient.

Table 4 Model summary and analysis of variance

	Model summary			ANOVA for SDS scores
	R	R2	Adjustment R2	Quadratic sum	Mean square	F value	P value
Model summary value	0.734	0.539	0.520	-	-	-	-
Regression	-	-	-	896.064	149.344	29.385	< 0.001
Residual error	-	-	-	767.436	5.082	-	-
Total	-	-	-	1663.500	-	-	-

Analysis of variance used Sheehan Disability Scale score as the dependent variable. ANOVA: Analysis of variance; SDS: Sheehan Disability Scale.

Table 5 Areas under the curve for predicting social impairment in patients with residual depressive symptoms

Test result variable	AUC (95%CI)	SE	P value	Sensitivity (%)	Specificity (%)	Optimum cutoff value
Disease history	0.713 (0.525–0.900)	0.096	0.012	79.2	83.3	-
Medication compliance	0.559 (0.349–0.770)	0.107	0.040	61.8	87.5	-
Therapy method	0.684 (0.528–0.840)	0.080	0.026	76.8	82.6	-
Degree of somatic symptoms	0.729 (0.485–0.972)	0.124	0.008	81.7	83.3	-
Residual symptoms	0.668 (0.504–0.831)	0.083	0.034	63.6	86.7	-
Anxiety score	0.628 (0.492–0.764)	0.069	0.037	65.5	92.1	8.5

95%CI: 95% confidence interval; AUC: Area under the curve; SE: Standard error.