Observational Study
Copyright ©The Author(s) 2024.
World J Psychiatry. Sep 19, 2024; 14(9): 1346-1353
Published online Sep 19, 2024. doi: 10.5498/wjp.v14.i9.1346
Table 1 Detection results of myocardial enzymes in schizophrenic patients and healthy groups
Group
n
Aspartate transferase (IU/L)
Lactate dehydrogenase (IU/L)
Creatine kinase (IU/L)
Creatine kinase isoenzyme (ng/mL)
A-hydroxybutyrate dehydrogenase (IU/L)
Schizophrenia group28849.76 ± 25.56213.26 ± 40.21155.23 ± 55.9222.17 ± 7.64160.23 ± 30.67
Health group10027.41 ± 12.33172.71 ± 10.68100.34 ± 8.3714.23 ± 2.11125 ± 6.38
t value-8.4069.9569.77010.250 11.392
P value-< 0.001< 0.001< 0.001 < 0.001 < 0.001
Table 2 Expression level of myocardial enzymes in patients with different violent behaviors
Group
n
Aspartate transferase (IU/L)
Lactate dehydrogenase (IU/L)
Creatine kinase (IU/L)
Creatine kinase isoenzyme (ng/mL)
A-hydroxybutyrate dehydrogenase (IU/L)
Violence group12375.67 ± 12.46257.31 ± 15.43219.34 ± 6.6729.41 ± 6.23195.38 ± 3.62
Non-violent group16530.61 ± 12.43180.71 ± 11.34107.84 ± 9.3716.83 ± 2.34134.24 ± 5.28
t value-30.40048.566 112.418 23.795 110.493
P value-< 0.001 < 0.001 < 0.001 < 0.001 < 0.001
Table 3 Single factor analysis of influencing violence, n (%)
Factor
Violence group

Non-violent group
t/χ²
P value
GenderMen 54 (43.90) 75 (45.45) 0.0690.793
Women69 (56.10) 90 (54.55)
Married65 (52.84) 89 (53.94) 0.0340.854
Inoccupation77 (62.60) 97 (58.79) 0.4290.513
Introverted71 (57.72) 90 (54.55) 0.2890.591
Irritability75 (60.98) 62 (37.58) 15.4710.000
Involuntary admission50 (40.65) 79 (47.88) 1.4890.222
Major life events56 (45.53) 74 (44.85) 0.0130.909
Depressed66 (53.66) 94 (56.97) 0.3130.576
Previous aggressive behavior93 (75.61) 66 (40.00) 36.1350.000
Anxious1.58 ± 0.941.65 ± 1.120.5610.575
Adopt a hostile attitude towards3.04 ± 1.072.87 ± 1.081.3270.186
Be suspicious3.65 ± 1.453.19 ± 1.562.5500.011
Hallucination3.38 ± 1.683.15 ± 1.581.1890.235
Behavior disorder3.36 ± 1.393.14 ± 1.251.4080.160
Drinking history54 (43.90) 58 (35.15) 2.2710.132
Smoking history59 (47.97) 61 (36.97) 3.5070.061
Number of hospitalization≤ 3 times76 (61.79) 119 (72.12) 3.4410.064
> 3 times47 (38.21) 46 (27.88)
Course of a disease< 6 months22 (17.89) 49 (29.70) 5.4410.066
6-12months54 (43.90) 59 (35.76)
> 12months47 (38.21) 57 (34.54)
Personality characteristicsIntrovert40 (32.52) 62 (37.57) 3.4090.182
Extroverted30 (24.39) 26 (15.76)
Intermediate personality53 (43.09) 77 (46.67)
Aspartate transferase (IU/L) 75.67 ± 12.4630.61 ± 12.4330.400< 0.001
Lactate dehydrogenase (IU/L) 257.31 ± 15.43180.71 ± 11.3448.566< 0.001
Creatine kinase (IU/L) 219.34 ± 6.67107.84± 9.37112.418< 0.001
Creatine kinase isoenzyme (ng/mL) 29.41 ± 6.2316.83 ± 2.3423.795< 0.001
A-hydroxybutyrate dehydrogenase (IU/L) 195.38 ± 3.62134.24 ± 5.28110.493< 0.001
Table 4 Logistic multivariate analysis of violent behavior in schizophrenic patients
Variable
B
SE
Wals
P value
Exp(B)
95%CI

Irritability0.3880.9910.1530.6961.4740.21110.286
Previous aggressive behavior1.1170.5643.9200.0483.0541.0119.225
Aspartate transferase (IU/L) 0.1690.02163.7480.0001.1841.1361.235
Lactate dehydrogenase (IU/L) -0.0290.0350.6780.4100.9710.9061.041
Creatine kinase (IU/L) 0.0910.0328.2390.0041.0951.0291.165
Creatine kinase isoenzyme (ng/mL) 0.3730.09316.0090.0001.4521.2101.744
A-hydroxybutyrate dehydrogenase (IU/L) 0.0420.1130.1380.7111.0430.8351.302
Constant-19.68522.6000.7590.3840.000
Table 5 Diagnostic value analysis
Index
Areas under the curve
Sensitivity
Specificity
95%CI
Youden's index
Previous aggressive behavior0.65072.4057.600.586-0.7140.300
Aspartate transferase (IU/L)0.93089.4089.700.899-0.9620.791
Creatine kinase (IU/L) 0.91391.1093.300.874-0.9520.844
Creatine kinase isoenzyme (ng/mL) 0.90987.8087.300.872-0.9470.751