Expression level of myocardial enzymes in patients with schizophrenia: Predictive value in the occurrence of violence

Abstract

BACKGROUND

Schizophrenic patients are prone to violence, frequent recurrence, and difficult to predict. Emotional and behavioral abnormalities during the onset of the disease, resulting in active myocardial enzyme spectrum.

AIM

To explored the expression level of myocardial enzymes in patients with schizophrenia and its predictive value in the occurrence of violence.

METHODS

A total of 288 patients with schizophrenia in our hospital from February 2023 to January 2024 were selected as the research object, and 100 healthy people were selected as the control group. Participants’ information, clinical data, and laboratory examination data were collected. According to Modified Overt Aggression Scale score, patients were further divided into the violent (123 cases) and non-violent group (165 cases).

RESULTS

The comparative analysis revealed significant differences in serum myocardial enzyme levels between patients with schizophrenia and healthy individuals. In the schizophrenia group, the violent and non-violent groups also exhibited different levels of serum myocardial enzymes. The levels of myocardial enzymes in the non-violent group were lower than those in the violent group, and the patients in the latter also displayed aggressive behavior in the past.

CONCLUSION

Previous aggressive behavior and the level of myocardial enzymes are of great significance for the diagnosis and prognosis analysis of violent behavior in patients with schizophrenia. By detecting changes in these indicators, we can gain a more comprehensive understanding of a patient’s condition and treatment.

Keywords: Schizophrenia; Myocardial enzyme index; Act of violence; Predict; Violence prediction; Aggressive behavior; Clinical data analysis; Biochemical markers

Core Tip: This study analyzes the expression levels of myocardial enzymes in patients with schizophrenia and explores their predictive value for violent behavior. The study involved 288 cases. The study was reviewed and approved by the Shaoxing Seventh Hospital Medical Ethics Committee. Patients with schizophrenia and 100 healthy controls, and patients were divided into violent and non-violent groups based on Modified Overt Aggression Scale scores. The results showed that there was a significant difference in serum myocardial enzyme levels between patients with schizophrenia and healthy individuals, and the myocardial enzyme levels in the violent group were higher than those in the non-violent group. Previous aggressive behavior and myocardial enzyme levels are of great value for diagnosis and prognosis analysis. By monitoring these indicators, we can have a more comprehensive understanding of the patient's condition and treatment progress, providing important references for clinical management.