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Observational Study
©Author(s) (or their employer(s)) 2026.
World J Psychiatry. Mar 19, 2026; 16(3): 114719
Published online Mar 19, 2026. doi: 10.5498/wjp.v16.i3.114719
Figure 1
Figure 1 Flow diagram illustrating participant selection and exclusion criteria for the study. MINI-KID: Mini International Neuropsychiatric Interview for children; HAMD-17: 17-item Hamilton Depression Rating Scale; MRI: Magnetic resonance imaging.
Figure 2
Figure 2 Voxel-wise comparison of cerebral blood flow in the right insular cortex between baseline and post-treatment with sertraline. Significant decreases were observed in the right insula (P < 0.001, family-wise type I error rate: Corrected).
Figure 3
Figure 3 Relationship between baseline right insular cortex cerebral blood flow and changes in 17-item Hamilton Depression Rating Scale scores post-treatment. CBF: Cerebral blood flow; HAMD: Hamilton Depression Rating Scale.