Sodium channel mutation SCN1A T875M, D188V and associated dysfunction with drug resistant epilepsy

doi:10.5498/wjp.v15.i2.100738

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Feb 19, 2025 (publication date) through Nov 4, 2025

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Feb 19, 2025; 15(2): 100738
Published online Feb 19, 2025. doi: 10.5498/wjp.v15.i2.100738

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Figure 1 Allele-specific polymerase chain reaction for SCN1A rs121917953 T/A* (D188V) polymorphism. Allele-specific PCR products electrophoresed on 2% agarose gel. Lane 1 to 7 (from left to right): Lane 1: 100 bp DNA ladder; Lane 2 and 3: Homozygous mutant genotype (232 bp); Lanes 4 and 5: Homozygous mutant genotypes (232 bp); Lane 6 and 7: Heterozygous genotype. WT: Wild-type forward primer (D188V); MT: Mutant forward primer (D188V).

Citation: Dabla PK, Gupta S, Singh S, Viswas A, Yadav M, Sonkar SC, Koner BC. Sodium channel mutation SCN1A T875M, D188V and associated dysfunction with drug resistant epilepsy. World J Psychiatry 2025; 15(2): 100738
URL: https://www.wjgnet.com/2220-3206/full/v15/i2/100738.htm
DOI: https://dx.doi.org/10.5498/wjp.v15.i2.100738