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World J Psychiatry. Jul 19, 2026; 16(7): 117143
Published online Jul 19, 2026. doi: 10.5498/wjp.117143
Published online Jul 19, 2026. doi: 10.5498/wjp.117143
Prevalence and treatment gap of comorbid depression and anxiety in elderly patients with hemodialysis
Lan Shen, Jing-Yi Ni, Department of Emergency Medicine, Hospital of Honghe State Affiliated to Kunming Medical University, Gejiu 661199, Yunnan Province, China
Ze-Yuan Pan, Department of Psychology Section, Hospital of Honghe State Affiliated to Kunming Medical University, Gejiu 661199, Yunnan Province, China
Yu-Jun Dai, Yan-Jun She, Xue-Mei He, Nephrology Hemodialysis Center, Hospital of Honghe State Affiliated to Kunming Medical University, Gejiu 661199, Yunnan Province, China
Co-first authors: Lan Shen and Jing-Yi Ni.
Co-corresponding authors: Yan-Jun She and Xue-Mei He.
Author contributions: Shen L and Ni JY are responsible for data collection and analysis, as well as writing the initial draft of the paper as co-first authors; Pan ZY and Dai YJ participated in data processing; She YJ and He XM are mainly responsible for the overall conceptual design, research process guidance, paper revision, and final draft of the research topic as co-corresponding authors; all authors have read and approved the final version of the paper.
AI contribution statement: ChatGPT, Grammarly, DeepL and other AI tools were not used in this study. The full text and any part of the manuscript were completely written by the authors without AI generation. No AI tools were applied for language polishing, translation, data analysis or writing assistance. AI tools did not participate in study design or result interpretation. All manuscript images were created by the authors, with no AI-generated pictures.
Supported by Chinese Association of Gerontology and Geriatrics, No. CAGG2025ZX013, No. CAGG2025ZX041, No. CAGG2025093, and No. CAGG2025132.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of Hospital of Honghe State Affiliated to Kunming Medical University, No. (2025) Yun Dian Nan Lun Shen (117).
Informed consent statement: All participants provided informed consent.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Data sharing statement: No additional data are available.
Corresponding author: Yan-Jun She, Chief Physician, Nephrology Hemodialysis Center, Hos
Received: January 16, 2026
Revised: February 10, 2026
Accepted: March 16, 2026
Published online: July 19, 2026
Processing time: 163 Days and 11.3 Hours
Revised: February 10, 2026
Accepted: March 16, 2026
Published online: July 19, 2026
Processing time: 163 Days and 11.3 Hours
Core Tip
Core Tip: Among elderly patients with hemodialysis, the prevalence of depression and anxiety was 38.0 %, with 65.8 % exhibiting a treatment gap. Female sex, living alone, longer hemodialysis duration, hypoalbuminemia, and higher Charlson Comorbidity Index scores were risk factors, whereas a confirmed psychiatric diagnosis significantly reduced the treatment gap.