Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Psychiatry. Jul 19, 2026; 16(7): 116727
Published online Jul 19, 2026. doi: 10.5498/wjp.116727
Published online Jul 19, 2026. doi: 10.5498/wjp.116727
Clinical mechanisms of continuous stellate ganglion block in improving postoperative anxiety and depression after thoracoscopic lung cancer surgery
Xuan Liu, Xiao-Jia Sun, Ye-Ming Wang, Department of Anesthesiology, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei Province, China
Wei Jing, Lu Zhang, Operating Room, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei Province, China
Author contributions: Liu X, Sun XJ, and Zhang L collected the data; Liu X and Sun XJ contributed to clinical investigation; Liu X and Jing W analyzed the data; Liu X designed the study and drafted the manuscript; Jing W and Wang YM revised the manuscript; Wang YM supervised the study and obtained funding; All authors approved the final manuscript and take responsibility for the integrity of the work.
Supported by the 2026 Hebei Provincial Medical Science Research Program, No. 20260801.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the First Affiliated Hospital of Hebei North University, approval No. K2025129.
Informed consent statement: The requirement for informed consent was waived due to the retrospective nature of the study and the use of anonymized clinical data.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The data supporting the findings of this study are available from the corresponding author upon reasonable request.
Corresponding author: Ye-Ming Wang, Associate Chief Physician, Department of Anesthesiology, The First Affiliated Hospital of Hebei North University, No. 12 Changqing Road, Zhangjiakou 075000, Hebei Province, China. hbbfxyfsdyyywym@163.com
Received: November 28, 2025
Revised: December 27, 2025
Accepted: April 2, 2026
Published online: July 19, 2026
Processing time: 210 Days and 10.4 Hours
Revised: December 27, 2025
Accepted: April 2, 2026
Published online: July 19, 2026
Processing time: 210 Days and 10.4 Hours
Core Tip
Core Tip: In this study, we demonstrated that continuous stellate ganglion block (CSGB) was more effective than sham-CSGB in reducing postoperative anxiety and depression in patients with thoracoscopic lung cancer surgery. In summary, CSGB has dual physical-psychological benefits through the modulation of sympathetic nervous system, surgical pain relief, sleep quality improvement and early mobilization. CSGB emerges as a potential adjunct within enhanced recovery pathways, providing an innovative opportunity for optimal physiological and emotional outcomes and earlier postoperative recovery.