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Retrospective Cohort Study
Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Psychiatry. Jun 19, 2026; 16(6): 116925
Published online Jun 19, 2026. doi: 10.5498/wjp.v16.i6.116925
Association of preoperative depression and cognitive status with postoperative delirium in elderly patients with hip fracture
Jie-Lin Zhong, Ying Cai, Shu-Hua Li, Wei Zhao, Xiao-Tian Su, Cheng-Hao Jin
Jie-Lin Zhong, Ying Cai, Xiao-Tian Su, Cheng-Hao Jin, Fourth Department of Orthopaedics, Tianjin Binhai New Area TEDA Hospital, Tianjin 300457, China
Shu-Hua Li, Department of Psychological, Tianjin Binhai New Area TEDA Hospital, Tianjin 300457, China
Wei Zhao, Department of Neurology, Tianjin Binhai New Area TEDA Hospital, Tianjin 300457, China
Author contributions: Zhong JL drafted the initial manuscript, designed the research study, coordinated the project, and served as both the first author and corresponding author; Cai Y contributed to the study design and methodology; Li SH and Zhao W contributed to data interpretation and provided critical revisions to the manuscript; Su XT and Jin CH collected the clinical data and performed the data analysis; all authors have read and approved the final manuscript.
Institutional review board statement: The study was approved by the Institutional Review Board of Tianjin Binhai New Area TEDA Hospital, No. 2025-11.
Informed consent statement: Due to the retrospective nature of the study, the ethics committee agreed to waive the informed consent form.
Conflict-of-interest statement: All authors declare that there are no conflicts of interest.
STROBE statement: The authors have read the STROBE Statement – checklist of items, and the manuscript was prepared and revised according to the STROBE Statement – checklist of items.
Data sharing statement: No available data.
Corresponding author: Jie-Lin Zhong, MD, Fourth Department of Orthopaedics, Tianjin Binhai New Area TEDA Hospital, No. 65 Third Street, Taida Street, Binhai New Area, Tianjin 300457, China. zjl13752737304@163.com
Received: January 6, 2026
Revised: January 26, 2026
Accepted: March 2, 2026
Published online: June 19, 2026
Processing time: 142 Days and 1.2 Hours
Core Tip

Core Tip: Cognitive dysfunction and preoperative depression were recognized as independent variables and were evaluated for the incidence of postoperative delirium in hip fracture surgery patients in the geriatric population. We have shown a considerable increase in the incidence of postoperative delirium with the combination of dementia and depression in this population via established techniques including the 15-item Geriatric Depression Scale, the Mini-Mental State Examination, and the Confusion Assessment Method. Higher American Society of Anesthesiologists scores and older age only increase the incidence. The incorporation of these screening mechanisms in the preoperative settings is expected to help construction of specific preoperative plans for patients at higher risk.

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