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World J Psychiatry. Jun 19, 2026; 16(6): 116809
Published online Jun 19, 2026. doi: 10.5498/wjp.v16.i6.116809
Published online Jun 19, 2026. doi: 10.5498/wjp.v16.i6.116809
Impact of depression and/or anxiety on accelerated lung function decline in patients with chronic obstructive pulmonary disease
Chen-Hui Ma, Cai-Hua Wang, Chen Yang, Mao Huang, Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, Jiangsu Province, China
Chen-Hui Ma, Department of Respiratory and Critical Care Medicine, Wuxi No. 2 People’s Hospital, Wuxi 214002, Jiangsu Province, China
Author contributions: Ma CH responsible for research design and paper writing; Wang CH and Yang C conducted data collection and analysis; Huang M is responsible for research guidance and paper review. All authors have read and agreed to the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of Wuxi No. 2 People’s Hospital (Approval No. WXEY-2026-21).
Informed consent statement: All study participants and their legal guardians provided written informed consent before recruitment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Corresponding author: Mao Huang, MD, Chief Physician, Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Gulou District, Nanjing 210000, Jiangsu Province, China.
Received: December 16, 2025
Revised: January 19, 2026
Accepted: March 4, 2026
Published online: June 19, 2026
Processing time: 163 Days and 0.7 Hours
Revised: January 19, 2026
Accepted: March 4, 2026
Published online: June 19, 2026
Processing time: 163 Days and 0.7 Hours
Core Tip
Core Tip: It has been demonstrated by this retrospective study that a significantly faster decline in forced expiratory volume in one second is experienced by patients with chronic obstructive pulmonary disease and comorbid depression and/or anxiety compared with those without psychological comorbidities. These findings highlight that psychological well-being is an independent hazard for the advancement of chronic obstructive pulmonary disease and should be incorporated into all-encompassing disease management tactics.