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World J Psychiatry. May 19, 2026; 16(5): 119366
Published online May 19, 2026. doi: 10.5498/wjp.v16.i5.119366
Published online May 19, 2026. doi: 10.5498/wjp.v16.i5.119366
Correlation between social alienation and psychological resilience in patients with multidrug-resistant organism infections under protective isolation
Mei Song, Fu-Jian Yan, Wei Shen, Jia Han, Department of Infectious Diseases, The First People’s Hospital of Jiashan/Jiashan Branch of the Second Affiliated Hospital of Zhejiang University School of Medicine, Jiaxing 314100, Zhejiang Province, China
Yu-Qin Liu, Department of Psychology, The First People’s Hospital of Jiashan/Jiashan Branch of the Second Affiliated Hospital of Zhejiang University School of Medicine, Jiaxing 314100, Zhejiang Province, China
Si-Yu Mao, Department of Laboratory Medicine, The First People’s Hospital of Jiashan/Jiashan Branch of the Second Affiliated Hospital of Zhejiang University School of Medicine, Jiaxing 314100, Zhejiang Province, China
Author contributions: Song M conceived and designed the study, supervised the overall research process, and drafted the manuscript; Yan FJ, Shen W, and Han J participated in data collection, patient screening, and clinical data verification; Liu YQ was responsible for psychological assessment implementation and scoring of the General Alienation Scale and Connor-Davidson Resilience Scale instruments; Mao SY contributed to laboratory data extraction and multidrug-resistant organisms infection confirmation; all authors reviewed and approved the final version of the manuscript.
Institutional review board statement: This study was reviewed and approved by the Medical Ethics Committee of The First People’s Hospital of Jiashan/Jiashan Branch of the Second Affiliated Hospital of Zhejiang University School of Medicine (No. 2025-106).
Informed consent statement: The requirement for written informed consent was waived by the Medical Ethics Committee of The First People’s Hospital of Jiashan/Jiashan Branch of the Second Affiliated Hospital of Zhejiang University School of Medicine (No. 2025-106), as this was a retrospective study based on anonymized data obtained from routine clinical records and involved no additional risk to patients.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
Data sharing statement: De-identified participant data are available from the corresponding author (songmeiarticle@163.com) upon reasonable request.
Corresponding author: Mei Song, Department of Infectious Diseases, The First People’s Hospital of Jiashan/Jiashan Branch of the Second Affiliated Hospital of Zhejiang University School of Medicine, No. 1218 Tiyu South Road, Jiaxing 314100, Zhejiang Province, China.
Received: March 6, 2026
Revised: April 9, 2026
Accepted: April 24, 2026
Published online: May 19, 2026
Processing time: 54 Days and 1.5 Hours
Revised: April 9, 2026
Accepted: April 24, 2026
Published online: May 19, 2026
Processing time: 54 Days and 1.5 Hours
Core Tip
Core Tip: Patients with multidrug-resistant organism infections often undergo protective isolation, which may adversely affect their psychosocial well-being. This study demonstrates that social alienation is prevalent among isolated patients and is moderately negatively correlated with psychological resilience. Lower family visit frequency, prolonged isolation, and lower educational level were associated with higher alienation, while greater tenacity and optimism were protective factors. These findings highlight the importance of integrating resilience-enhancing psychological interventions into the care of patients under protective isolation.