©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Jan 19, 2026; 16(1): 113965
Published online Jan 19, 2026. doi: 10.5498/wjp.v16.i1.113965
Published online Jan 19, 2026. doi: 10.5498/wjp.v16.i1.113965
Inflammation and suicide risk in adolescents with self-injury: Expanding the role of mental health nursing
Giuliano Anastasi, Department of Trauma, Azienda Ospedaliera Universitaria Gaetano Martino-Messina, Messina 98121, Sicilia, Italy
Author contributions: Anastasi G conceptualized and wrote the paper.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Giuliano Anastasi, PhD, Adjunct Professor, Department of Trauma, Azienda Ospedaliera Universitaria Gaetano Martino-Messina, No. 1 Via Consolare Valeria, Messina 98121, Sicilia, Italy. giuliano.anastasi@polime.it
Received: September 8, 2025
Revised: October 21, 2025
Accepted: October 29, 2025
Published online: January 19, 2026
Processing time: 114 Days and 15.9 Hours
Revised: October 21, 2025
Accepted: October 29, 2025
Published online: January 19, 2026
Processing time: 114 Days and 15.9 Hours
Core Tip
Core Tip: Inflammatory biomarkers, such as interleukin-10 and interferon-α, have been associated with suicide risk among adolescents with self-injury, offering a biological complement to psychosocial assessment. However, translating these biological profiles into clinical practice will require specialized healthcare workers. Empowering mental health nurses to integrate biomarker monitoring with structured nursing assessment can transform laboratory findings into practical, equitable, and sustainable strategies for adolescent suicide prevention.