Zhao W, Chen WG, Zhang LY, Cui ZM, Wang XJ. Impact of depression, anxiety, inflammatory factors, and stress levels on treatment outcomes in patients with chronic trauma. World J Psychiatry 2025; 15(3): 103250 [DOI: 10.5498/wjp.v15.i3.103250]
Corresponding Author of This Article
Xue-Jian Wang, MD, PhD, Department of Neurosurgery, Affiliated Hospital 2 of Nantong University, No. 666 Shengli Road, Chongchuan District, Nantong 226000, Jiangsu Province, China. 6841441@163.com
Research Domain of This Article
Psychiatry
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Psychiatry. Mar 19, 2025; 15(3): 103250 Published online Mar 19, 2025. doi: 10.5498/wjp.v15.i3.103250
Impact of depression, anxiety, inflammatory factors, and stress levels on treatment outcomes in patients with chronic trauma
Wei Zhao, Wei-Guan Chen, Long-Yao Zhang, Zhi-Ming Cui, Xue-Jian Wang
Wei Zhao, Long-Yao Zhang, Xue-Jian Wang, Department of Neurosurgery, Affiliated Hospital 2 of Nantong University, Nantong 226000, Jiangsu Province, China
Wei-Guan Chen, Department of Rehabilitation Medicine, Affiliated Hospital 2 of Nantong University, Nantong 226000, Jiangsu Province, China
Zhi-Ming Cui, Department of Orthopedics, Affiliated Hospital 2 to Nantong University, Nantong 226001, Jiangsu Province, China
Co-first authors: Wei Zhao and Wei-Guan Chen.
Co-corresponding authors: Zhi-Ming Cui and Xue-Jian Wang.
Author contributions: Wang XJ wrote the article; Zhao W and Zhang LY sorted out the data and summarized the literature; Chen WG revised the article; Cui ZM reviewed the manuscript. Zhao W and Chen WG did the work related to data sorting and document preparation and contributed equally to this manuscript as co-first authors; Cui ZM and Wang XJ wrote and organized the manuscript and eventually published it and contributed equally to this manuscript as co-corresponding authors.
Supported by Research Project of Nantong Health and Health Commission, No. MS2023041 and No. MA2021017; Science and Technology Program of Nantong City, No. Key03 and No. JCZ2022040; Kangda College of Nanjing Medical University, No. KD2021JYYJYB025, No. KD2022KYJJZD019, and No. KD2022KYJJZD022; and Nantong Young Medical Expert, No. 46.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xue-Jian Wang, MD, PhD, Department of Neurosurgery, Affiliated Hospital 2 of Nantong University, No. 666 Shengli Road, Chongchuan District, Nantong 226000, Jiangsu Province, China. 6841441@163.com
Received: November 13, 2024 Revised: December 15, 2024 Accepted: January 13, 2025 Published online: March 19, 2025 Processing time: 105 Days and 5.6 Hours
Core Tip
Core Tip: With the development of technology and society, the incidence of chronic wounds is on the rise. At present, chronic wounds have become a common clinical problem that affects health and causes economic burden. What patients with chronic trauma experience is not only physical pain, but also psychological problems such as depression and anxiety, as well as changes in inflammatory factors and stress levels in peripheral blood. These factors are intertwined and jointly affect the whole process of treatment. Nowadays, with the continuous progress in the medical field, our treatment and care for chronic trauma patients should not only be limited to the repair of physical injury, but also should deeply explore the impact of their comprehensive psychological and physiological conditions on the treatment results.
