Wang XL, Zhao YR, Yu Y, Mao ZF, Tan SX, Yu SS. Impact of dietary nutrition regimens based on body composition analysis on bone metabolism in Alzheimer’s disease patients. World J Psychiatry 2025; 15(2): 99008 [DOI: 10.5498/wjp.v15.i2.99008]
Corresponding Author of This Article
Shan-Shan Yu, BMed, Doctor, Department of Geriatric Psychiatry, The Third Hospital of Quzhou, No. 226 Baiyun North Avenue, Baiyun Street, Kecheng District, Quzhou 324000, Zhejiang Province, China. 17015041@qq.com
Research Domain of This Article
Geriatrics & Gerontology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Xue-Lian Wang, Department of Clinical Nutrition, The Third Hospital of Quzhou, Quzhou 324000, Zhejiang Province, China
Yi-Ran Zhao, Department of Rehabilitation Treatment Group, The Third Hospital of Quzhou, Quzhou 324000, Zhejiang Province, China
Ying Yu, Department of Geriatrics, The Third Hospital of Quzhou, Quzhou 324000, Zhejiang Province, China
Zhi-Fang Mao, Department of Rehabilitation Medicine, The Third Hospital of Quzhou, Quzhou 324000, Zhejiang Province, China
Su-Xian Tan, Department of Psychiatry, The Third Hospital of Quzhou, Quzhou 324000, Zhejiang Province, China
Shan-Shan Yu, Department of Geriatric Psychiatry, The Third Hospital of Quzhou, Quzhou 324000, Zhejiang Province, China
Co-first authors: Xue-Lian Wang and Yi-Ran Zhao.
Author contributions: Wang XL and Zhao YR contributed equally to this work and are co-first authors; Wang XL and Zhao YR designed the research, wrote the first manuscript, and conducted the analysis and provided guidance for the research; Wang XL, Zhao YR, Yu Y, Mao ZF, Tan SX and Yu SS contributed to conceiving the research and analyzing data; All authors reviewed and approved the final manuscript.
Supported by Science and Technology Bureau of Quzhou, No. 2022079.
Institutional review board statement: This study was approved by the Ethic Committee of The Third Hospital of Quzhou (No. SY-2022-09).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shan-Shan Yu, BMed, Doctor, Department of Geriatric Psychiatry, The Third Hospital of Quzhou, No. 226 Baiyun North Avenue, Baiyun Street, Kecheng District, Quzhou 324000, Zhejiang Province, China. 17015041@qq.com
Received: October 11, 2024 Revised: November 27, 2024 Accepted: December 17, 2024 Published online: February 19, 2025 Processing time: 95 Days and 0.9 Hours
Core Tip
Core Tip: Body composition analysis (BCA) is primarily used in the management of conditions such as obesity and endocrine disorders. However, its potential in providing nutritional guidance for patients with Alzheimer’s disease (AD) remains relatively unexplored. In this study, we found that both routine diet (RD) and personalized nutritional (PN) interventions significantly increased bone mineral density (BMD) and improved bone metabolism indexes in AD patients compared to baseline levels. Furthermore, PN intervention, which is based on human BCA, provided superior bone outcomes compared to RD, as evidenced by higher BMD and better bone metabolic indexes in the PN group. These findings provide strong research evidence supporting the development of targeted nutritional interventions for AD patients.
