Byeon H. Synthesizing the risk of postoperative delirium in organ transplantation. World J Psychiatry 2025; 15(11): 113121 [DOI: 10.5498/wjp.v15.i11.113121]
Corresponding Author of This Article
Haewon Byeon, PhD, Associate Professor, Director, Worker's Care and Digital Health Laboratory, Department of Future Technology, Korea University of Technology and Education, 1600 Chungjeol-ro, Cheonan 31253, South Korea. bhwpuma@naver.com
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Psychiatry
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Letter to the Editor
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Nov 19, 2025 (publication date) through Nov 4, 2025
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Publication Name
World Journal of Psychiatry
ISSN
2220-3206
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Byeon H. Synthesizing the risk of postoperative delirium in organ transplantation. World J Psychiatry 2025; 15(11): 113121 [DOI: 10.5498/wjp.v15.i11.113121]
World J Psychiatry. Nov 19, 2025; 15(11): 113121 Published online Nov 19, 2025. doi: 10.5498/wjp.v15.i11.113121
Synthesizing the risk of postoperative delirium in organ transplantation
Haewon Byeon
Haewon Byeon, Worker's Care and Digital Health Laboratory, Department of Future Technology, Korea University of Technology and Education, Cheonan 31253, South Korea
Author contributions: Byeon H designed the study, was responsible for data interpretation and writing the article.
Supported by National Research Foundation of Korea, No. RS-2023-00237287.
Conflict-of-interest statement: The author declares no conflict of interest in publishing the manuscript.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Haewon Byeon, PhD, Associate Professor, Director, Worker's Care and Digital Health Laboratory, Department of Future Technology, Korea University of Technology and Education, 1600 Chungjeol-ro, Cheonan 31253, South Korea. bhwpuma@naver.com
Received: August 15, 2025 Revised: September 8, 2025 Accepted: October 11, 2025 Published online: November 19, 2025 Processing time: 80 Days and 23.3 Hours
Core Tip
Core Tip: The meta-analysis by Hou et al provides a crucial summary, establishing a 20% overall incidence of postoperative delirium in organ transplant patients, with rates varying significantly by organ. Key risk factors identified, such as primary graft dysfunction and high model for end-stage liver disease/acute physiology and chronic health evaluation II scores, offer actionable targets for clinical prevention. However, the study's substantial heterogeneity and the unexpected non-significance of age as a risk factor highlight the limitations of pooling diverse studies. This commentary emphasizes that while the meta-analysis is a valuable evidence synthesis, its findings should be interpreted with caution, paving the way for future prospective, organ-specific research with standardized protocols to develop robust clinical tools.