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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Nov 19, 2025; 15(11): 108688
Published online Nov 19, 2025. doi: 10.5498/wjp.v15.i11.108688
Published online Nov 19, 2025. doi: 10.5498/wjp.v15.i11.108688
Influencing factors and construction of a nomogram for post-stroke depression in patients with chronic stroke
Zheng Han, Ni-Ni Li, Department of Neurology, Shaanxi Provincial People's Hospital, Xi’an 710068, Shaanxi Province, China
Dong-Dong Zhang, Department of Neurosurgery, Norinco General Hospital, Xi’an 710065, Shaanxi Province, China
Author contributions: Han Z contributed to conceptualization, methodology, data statistics and analysis, writing-original draft preparation, and review of the manuscript.; Han Z and Zhang DD contributed to case collection and collation; Li NN contributed to supervision.
Institutional review board statement: This study was approved by the Ethics Committee of Shaanxi Provincial People's Hospital.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All authors declare no conflicts of interest.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ni-Ni Li, Department of Neurology, Shaanxi Provincial People's Hospital, No. 256 West Youyi Road, Xi’an 710068, Shaanxi Province, China.
Received: June 17, 2025
Revised: August 7, 2025
Accepted: September 2, 2025
Published online: November 19, 2025
Processing time: 139 Days and 17.5 Hours
Revised: August 7, 2025
Accepted: September 2, 2025
Published online: November 19, 2025
Processing time: 139 Days and 17.5 Hours
Core Tip
Core Tip: This study centers on identifying contributors to post-stroke depression (PSD) in patients with chronic stroke and establishing a relevant nomogram. Based on the results of various analytical procedures, individuals with lower educational attainment, and high neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio are at greater risk of PSD. Tailored clinical interventions, along with vigilant monitoring, can effectively mitigate PSD risk in patients presenting these features. The nomogram shows strong predictive accuracy for high-risk groups; however, its reliability slightly decreases for low- and intermediate-risk groups.