Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Nov 19, 2025; 15(11): 108686
Published online Nov 19, 2025. doi: 10.5498/wjp.v15.i11.108686
Published online Nov 19, 2025. doi: 10.5498/wjp.v15.i11.108686
Palliative treatment and social support needs in patients with liver, gallbladder, and pancreatic tumors
Xiao Yu, Cheng-Long Huo, Shuai Wang, Department of Hepatobiliary Surgery, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou 434020, Hubei Province, China
Co-first authors: Xiao Yu and Cheng-Long Huo.
Author contributions: Yu X and Huo CL contribute equally to this study as co-first authors; Yu X and Huo CL designed the study, performed the primary literature review and data extraction, analyzed the data and wrote the manuscript; Yu X and Wang L revised the manuscript for important intellectual content; all authors have read and approved the final version.
Institutional review board statement: This study was reviewed and approved by the Science and Research Office of Jingzhou Hospital Affiliated to Yangtze University (No. 2025-118-01).
Informed consent statement: All study participants or their legal guardians provided written informed consent for personal and medical data collection before enrollment. All collected data were de-identified and analyzed anonymously, and the study protocol complied with the ethical standards of the Declaration of Helsinki.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shuai Wang, Associate Chief Physician, Department of Hepatobiliary Surgery, Jingzhou Hospital Affiliated to Yangtze University, Chuyuan Avenue, Jingzhou District, Jingzhou 434020, Hubei Province, China. chenglonghuo123@126.com
Received: June 17, 2025
Revised: July 22, 2025
Accepted: August 25, 2025
Published online: November 19, 2025
Processing time: 139 Days and 17.8 Hours
Revised: July 22, 2025
Accepted: August 25, 2025
Published online: November 19, 2025
Processing time: 139 Days and 17.8 Hours
Core Tip
Core Tip: This mixed-methods study pioneered the integration of palliative care with structured psychosocial support for patients with end-stage hepatobiliary and pancreatic (HBP) cancer, demonstrating synergistic efficacy in alleviating depression–anxiety comorbidity. By establishing a multidimensional symptom management protocol (targeting neuroendocrine dysregulation and inflammatory cascades) and an interdisciplinary social support network (addressing existential distress and familial burden), the intervention achieved significant survival benefits alongside enhanced quality of life, redefining holistic care paradigms for terminal HBP malignancies.