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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Nov 19, 2025; 15(11): 108288
Published online Nov 19, 2025. doi: 10.5498/wjp.v15.i11.108288
Published online Nov 19, 2025. doi: 10.5498/wjp.v15.i11.108288
Efficacy of electroacupuncture for cervical spondylosis-related pain in patients with generalized anxiety disorder
Zhe Li, Department of Pain Disease Treatment, Zhengzhou Orthopaedic Hospital, Zhengzhou 450052, Henan Province, China
Yu Gao, Dong Yan, Department of Cervicolumbar, Zhengzhou Orthopaedic Hospital, Zheng
Yi-Hui Feng, Department of Acupuncture and Moxibustion, University of Health and Reha
Author contributions: Li Z and Gao Y was the guarantor and designed the study; Li Z, Yan D, and Feng YH participated in the acquisition, analysis, and interpretation of the data, and drafted the initial manuscript; Li Z, Feng YH, and Yan D revised the article critically for important intellectual content. All authors participated in this study and jointly reviewed and edited the manuscript.
Institutional review board statement: The research protocol was reviewed and approved by the Institutional Review Committee of Zhengzhou Orthopedic Hospital, No. IEC-2024-07.
Informed consent statement: The requirement for informed consent was waived because of the retrospective nature of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yi-Hui Feng, MD, Department of Acupuncture and Moxibustion, University of Health and Rehabilitation Sciences, No. 369 Dengyun Road, Qingdao High-tech Zone, Qingdao 266042, Shandong Province, China. walgzzh@126.com
Received: June 5, 2025
Revised: July 4, 2025
Accepted: August 26, 2025
Published online: November 19, 2025
Processing time: 150 Days and 23.1 Hours
Revised: July 4, 2025
Accepted: August 26, 2025
Published online: November 19, 2025
Processing time: 150 Days and 23.1 Hours
Core Tip
Core Tip: This study highlights the effectiveness of electroacupuncture (EA) in reducing cervical spondylosis-related pain and alleviating anxiety symptoms in patients with comorbid generalized anxiety disorders. Over an 8-week treatment period, EA significantly reduced pain, anxiety, and neuroinflammatory markers, such as interleukin-6 and tumor necrosis factor-alpha. These findings suggest that EA may be a promising integrative approach for managing both pain and anxiety by modulating neuroinflammatory pathways, offering valuable clinical benefits for patients with this complex condition.