Prospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Jun 19, 2024; 14(6): 938-944
Published online Jun 19, 2024. doi: 10.5498/wjp.v14.i6.938
Clinical efficacy of Baijin pills in the treatment of generalized tonic-clonic seizure epilepsy with cognitive impairment
Jing-Bo Li, Jing Jiang, Lian Xue, Shuai Zhao, Hong-Quan Liu
Jing-Bo Li, Jing Jiang, Lian Xue, Shuai Zhao, Hong-Quan Liu, Department of Neurology, The Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210000, Jiangsu Province, China
Jing-Bo Li, Jing Jiang, Lian Xue, Shuai Zhao, Hong-Quan Liu, Department of Neurology, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing 210000, Jiangsu Province, China
Author contributions: Li JB and Liu HQ contributed equally to this work; Li JB, Jiang J, Xue L, Zhao S and Liu HQ designed the research study; Li JB, Jiang J, Xue L, Zhao S and Liu HQ performed the research; Jiang J, Xue L, Zhao S contributed new reagents and analytic tools; Li JB and Liu HQ analyzed the data and wrote the manuscript; all authors have read and approve the final manuscript.
Supported by Jiangsu Province Phase 6 "333 Project", No. BRA202201.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Committee of the Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine Ethics Committee.
Clinical trial registration statement: Clinical trials registered in researchregistry (www.researchregistry.com).
Informed consent statement: All study participants, or their legal guardian, provided written consent prior to study enrollment.
Conflict-of-interest statement: Dr. Liu has nothing to disclose.
Data sharing statement: There is no additional data available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 Statement, and the manuscript was prepared and revised according to the CONSORT 2010 Statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hong-Quan Liu, MD, Chief Doctor, Chief Physician, Department of Neurology, The Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, No. 100 Cross Street, Hongshan Road, Nanjing 210000, Jiangsu Province, China. hongquanliu0305@163.com
Received: March 1, 2024
Revised: April 22, 2024
Accepted: April 25, 2024
Published online: June 19, 2024
Processing time: 110 Days and 5.3 Hours
Core Tip

Core Tip: Generalized tonic-clonic seizure can induce the most significant damage to cognitive function. The impact of antiepileptic drugs on cognition should not be ignored. At present, there is no special treatment for patients with epilepsy, and traditional Chinese medicine has shown a significant effect on chronic diseases with fewer harmful side effects; therefore, traditional Chinese medicine should be considered for the treatment of epilepsy with cognitive dysfunction. Baijin pills have a positive clinical effect on patients with epilepsy and cognitive dysfunction.