©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Feb 19, 2024; 14(2): 194-198
Published online Feb 19, 2024. doi: 10.5498/wjp.v14.i2.194
Published online Feb 19, 2024. doi: 10.5498/wjp.v14.i2.194
Keep in mind sex differences when prescribing psychotropic drugs
Marianna Mazza, Giuseppe Marano, Department of Neurosciences, Fondazione Policlinico Universitario A Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome 00168, Italy
Domenico De Berardis, Mental Health, NHS, ASL 4 Teramo, Teramo 64100, Italy
Author contributions: Mazza M, De Berardis D, and Marano G designed the research study and wrote the manuscript; and all authors have read and have approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Marianna Mazza, MD, PhD, Assistant Professor, Department of Neurosciences, Fondazione Policlinico Universitario A Gemelli IRCCS, Università Cattolica del Sacro Cuore, Largo A Gemelli 8, Rome 00168, Italy. mariannamazza@hotmail.com
Received: October 8, 2023
Peer-review started: October 8, 2023
First decision: November 30, 2023
Revised: December 2, 2023
Accepted: January 2, 2024
Article in press: January 2, 2024
Published online: February 19, 2024
Processing time: 120 Days and 22.4 Hours
Peer-review started: October 8, 2023
First decision: November 30, 2023
Revised: December 2, 2023
Accepted: January 2, 2024
Article in press: January 2, 2024
Published online: February 19, 2024
Processing time: 120 Days and 22.4 Hours
Core Tip
Core Tip: It has been largely demonstrated that women are the majority of patients with psychiatric diagnoses and also the largest users of psychotropic drugs. There are differences between men and women receiving psychotropic drugs, in terms of response, efficacy, side effects, long-term treatment outcome. There is still a lack of psychopharmacological research focusing on these differences in male and female patients. This editorial focuses on the important issue of deeply understanding the pharmacokinetics and pharmacodynamics of central nervous system drugs with a priority to differentiate between men and women in order to provide personalized management of care.