Systematic Reviews
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. May 19, 2023; 13(5): 247-261
Published online May 19, 2023. doi: 10.5498/wjp.v13.i5.247
Knowledge, attitudes and experiences of genetic testing for autism spectrum disorders among caregivers, patients, and health providers: A systematic review
Meng Zhou, Ya-Min Zhang, Tao Li
Meng Zhou, Ya-Min Zhang, Tao Li, Department of Neurobiology, Affiliated Mental Health Center & Hangzhou Seventh People’s Hospital, Zhejiang University School of Medicine, Hangzhou 310013, Zhejiang Province, China
Ya-Min Zhang, Tao Li, Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University, Hangzhou 310013, Zhejiang Province, China
Ya-Min Zhang, Tao Li, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University, Hangzhou 310013, Zhejiang Province, China
Author contributions: Zhou M and Zhang YM contributes equally to this paper. Zhang YM and Zhou M provide the conceptualization; Zhang YM and Zhou M contributed to the methodology, literature searching, data extraction; Li T contributed to the administration resources, and supervision; Zhou M contributed to writing the original draft; Zhang YM and Li T contributed to reviewing the draft; all authors have read and approved the final manuscript.
Supported by the National Natural Science Foundation of China, No. 81920108018 (Li T and Sham P), No. 82001409 (Zhang YM), the Key R & D Program of Zhejiang, No. 2022C03096 (Li T); Project for Hangzhou Medical Disciplines of Excellence.
Conflict-of-interest statement: There is no conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tao Li, MD, PhD, Academic Research, Professor, Department of Neurobiology, Affiliated Mental Health Center & Hangzhou Seventh People’s Hospital, Zhejiang University School of Medicine, No.305 Tianmushan Road, Hangzhou 310013, Zhejiang Province, China. litaozjusc@zju.edu.cn
Received: December 30, 2022
Peer-review started: December 30, 2022
First decision: March 1, 2023
Revised: March 10, 2023
Accepted: April 17, 2023
Article in press: April 17, 2023
Published online: May 19, 2023
Processing time: 140 Days and 8.8 Hours
Core Tip

Core Tip: More action should be taken to improve the knowledge level about genetic testing among caregivers of patients with autism spectrum disorder (ASD). Health education from health providers such as physicians and psychiatrists appear the most effective method. Improving the knowledge level of ASD genetic testing among health providers is necessary for better utilization of genetic testing in ASD practice. Caregivers of patients with ASD and patients themselves generally hold a positive attitude toward genetic testing. More comprehensive knowledge is needed to avoid potential misunderstandings.