Review
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Nov 19, 2023; 13(11): 816-830
Published online Nov 19, 2023. doi: 10.5498/wjp.v13.i11.816
Management of acute carbamazepine poisoning: A narrative review
Luan Wang, Yang Wang, Ruo-Ying Zhang, Yao Wang, Wei Liang, Tie-Gang Li
Luan Wang, Ruo-Ying Zhang, Yao Wang, Wei Liang, Tie-Gang Li, Department of Emergency Medicine, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China
Yang Wang, Department of General Surgery, The 4th Affiliated Hospital of China Medical University, Shenyang 110032, Liaoning Province, China
Author contributions: Wang L, Wang Y, Zhang RY, Wang Y, Liang W, and Li TG contributed to drafting and editing of the manuscript, and approved the final manuscript.
Supported by Science and Public Welfare Research Fund of Liaoning Province, No. 2022JH4/10100075; and National Nature Science Foundation of China, No. 81772056.
Conflict-of-interest statement: The authors declared that they have no conflicts of interest to this work. We declare that we do not have any commercial or associative interest that represents a conflict of interest in connection with the work submitted and entitled ‘Management of Acute Carbamazepine Poisoning: A Narrative Review’.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tie-Gang Li, MD, PhD, Professor, Department of Emergency Medicine, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang, Shenyang 110004, Liaoning Province, China. litg@sj-hospital.org
Received: September 5, 2023
Peer-review started: September 5, 2023
First decision: September 14, 2023
Revised: September 23, 2023
Accepted: October 11, 2023
Article in press: October 11, 2023
Published online: November 19, 2023
Processing time: 73 Days and 0.6 Hours
Core Tip

Core Tip: There is no effective Antidote and standard treatment management for carbamazepine (CBZ) poisoning. This paper describes and summarizes the detailed clinical evidence of the treatment and management of CBZ poisoning, including gastric lavage and activated carbon therapy, hemoplavage, hemodialysis, continuous renal replacement treatment and plasmapheresis. Finally, this paper also provides the lipid resuscitation therapy to provide help for clinical treatment. In general, this paper summarized the results of CBZ poisoning related research, and provided the best plan for CBZ poisoning treatment.