©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatr. Oct 19, 2021; 11(10): 696-710
Published online Oct 19, 2021. doi: 10.5498/wjp.v11.i10.696
Published online Oct 19, 2021. doi: 10.5498/wjp.v11.i10.696
Metabolic disturbances associated with antipsychotic drug treatment in patients with schizophrenia: State-of-the-art and future perspectives
Shen-Chieh Chang, Kah Kheng Goh, Mong-Liang Lu, Department of Psychiatry, Wan Fang Hospital, Taipei Medical University, Taipei 116, Taiwan
Kah Kheng Goh, Mong-Liang Lu, Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei 116, Taiwan
Author contributions: Chang SC and Goh KK contributed equally to this work; Chang SC, Goh KK, and Lu ML performed the literature search and reviewed the selected manuscripts; Chang SC wrote the first draft; Goh KK and Lu ML contributed to the final version of the manuscript; All authors have read and approve the final manuscript.
Supported by the Higher Education Sprout Project of the Ministry of Education , No. DP2-109-21121-01-N-07-04 ; and the Ministry of Science and Technology , No. MOST109-2314-B-038-083 .
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Corresponding author: Mong-Liang Lu, MD, MS, Professor, Department of Psychiatry, Wan Fang Hospital, Taipei Medical University, No. 111 Section 3, Hsin-Long Rd, Taipei 116, Taiwan. mongliang@hotmail.com
Received: January 30, 2021
Peer-review started: January 30, 2021
First decision: March 8, 2021
Revised: March 16, 2021
Accepted: August 31, 2021
Article in press: August 31, 2021
Published online: October 19, 2021
Processing time: 258 Days and 1.7 Hours
Peer-review started: January 30, 2021
First decision: March 8, 2021
Revised: March 16, 2021
Accepted: August 31, 2021
Article in press: August 31, 2021
Published online: October 19, 2021
Processing time: 258 Days and 1.7 Hours
Core Tip
Core Tip: Metabolic disturbances associated with antipsychotic drug treatment are prevalent in patients with schizophrenia. We herein discuss the epidemiology, the underlying mechanisms, monitoring, and intervention strategies of antipsychotics related metabolic disturbances.