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World Journal of Psychiatry
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2220-3206
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatr. Mar 22, 2015; 5(1): 1-3
Published online Mar 22, 2015. doi: 10.5498/wjp.v5.i1.1
Is lithium potentially a trace element?
Takeshi Terao
Takeshi Terao, Department of Neuropsychiatry, Oita University Faculty of Medicine, Hasama-machi, Yufu City, Oita Prefecture 879-5593, Japan
Author contributions: Terao T solely contributed to this paper.
Conflict-of-interest: In relation to the above manuscript, Takeshi Terao has no received fees for serving as a speaker, received no research funding, no stocks or no patent.
Correspondence to: Takeshi Terao, MD, PhD, Professor, Department of Neuropsychiatry, Oita University Faculty of Medicine, 1-1 Idaigaoka, Hasama-machi, Yufu City, Oita Prefecture 879-5593, Japan. terao@oita-u.ac.jp
Telephone: +81-97-5865823 Fax: +81-97-5493583
Received: November 23, 2014
Peer-review started: November 24, 2014
First decision: December 26, 2014
Revised: January 7, 2015
Accepted: February 4, 2015
Article in press: February 9, 2015
Published online: March 22, 2015
Processing time: 174 Days and 16.3 Hours
Abstract

Lithium, a naturally occurring element, is widely used in clinical settings for psychiatric treatment. Several studies showed that micro-dose lithium (e.g., lithium in drinking water) could have anti-aging and anti-dementia effects in addition to an anti-suicidal effect, although anti-mania and psychosis or anti-cancer effects are yet to be determined. Although these studies do not provide conclusive evidence, further studies are warranted to investigate whether lithium is trace element. If so, future studies would need to determine what levels are required to maintain mental health.

Keywords: Lithium; Trace element; Suicide; Micro-dose; Aging; Dementia

Core tip: Micro-dose lithium (e.g., lithium in drinking water) could have anti-aging and anti-dementia effects as well as anti-suicidal effect.
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