Wang L, Mei LN, Shen SJ, Shen GS. Effect of pre-pregnancy eugenics health examination and education on knowledge-belief-behavior, anxiety, risk-averse behavior childbearing-age women. World J Psychiatry 2026; 16(8): 120395 [DOI: 10.5498/wjp.120395]
Corresponding Author of This Article
Guo-Song Shen, Chief Physician, Medical Laboratory Center, Huzhou Maternity and Child Health Care Hospital, No. 2 East Street, Wuxing District, Huzhou 313000, Zhejiang Province, China. hzsfybjymln3769@126.com
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Psychology
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research-article
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Wang L, Mei LN, Shen SJ, Shen GS. Effect of pre-pregnancy eugenics health examination and education on knowledge-belief-behavior, anxiety, risk-averse behavior childbearing-age women. World J Psychiatry 2026; 16(8): 120395 [DOI: 10.5498/wjp.120395]
World J Psychiatry. Aug 19, 2026; 16(8): 120395 Published online Aug 19, 2026. doi: 10.5498/wjp.120395
Effect of pre-pregnancy eugenics health examination and education on knowledge-belief-behavior, anxiety, risk-averse behavior childbearing-age women
Li Wang, Li-Na Mei, Shu-Jun Shen, Guo-Song Shen
Li Wang, Shu-Jun Shen, Physical Examination Center, Huzhou Maternity and Child Health Care Hospital, Huzhou 313000, Zhejiang Province, China
Li-Na Mei, Department of Internal Medicine, Huzhou Maternity and Child Health Care Hospital, Huzhou 313000, Zhejiang Province, China
Guo-Song Shen, Medical Laboratory Center, Huzhou Maternity and Child Health Care Hospital, Huzhou 313000, Zhejiang Province, China
Co-corresponding authors: Li-Na Mei and Guo-Song Shen.
Author contributions: Wang L is responsible for the feasibility analysis of the research, as well as writing and revising the paper; Mei LN is in charge of data collection and statistical processing, and provides guidance for the feasibility analysis and implementation of the research; Shen SJ is responsible for data collection and collation; Shen GS is in charge of reviewing the presentation style of the paper, controlling the paper quality, and providing guidance for the implementation of the research; Mei LN and Shen GS are designed as co-corresponding authors; all authors reviewed and approved the final manuscript.
AI contribution statement: The authors declare that no AI tools were used in the development or writing of this manuscript and take full responsibility for its integrity, accuracy, and originality.
Supported by Huzhou Science and Technology Bureau, No. 2025GYB68.
Institutional review board statement: This study was approved by the Ethic Committee of Huzhou Maternity and Child Health Care Hospital.
Informed consent statement: All research subjects provided informed written consent regarding personal and medical data collection prior to enrollment in the study.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Data sharing statement: No additional data are available.
Corresponding author: Guo-Song Shen, Chief Physician, Medical Laboratory Center, Huzhou Maternity and Child Health Care Hospital, No. 2 East Street, Wuxing District, Huzhou 313000, Zhejiang Province, China. hzsfybjymln3769@126.com
Received: April 8, 2026 Revised: May 11, 2026 Accepted: May 26, 2026 Published online: August 19, 2026 Processing time: 100 Days and 2.8 Hours
Abstract
BACKGROUND
Pre-pregnancy eugenic health examination is a key measure for reducing the incidence of congenital malformations in newborns. However, pre-pregnancy adverse factors cannot be fully reduced or eliminated through examination alone. Therefore, it is particularly important to integrate education on reproductive health, eugenics, and pre-pregnancy care into pre-pregnancy health examinations.
AIM
To explore the effects of pre-pregnancy eugenic health examination and education on knowledge, attitude, and behavior, as well as anxiety and risk-aversion behavior in women of childbearing age.
METHODS
This retrospective study included women of childbearing age who received pre-pregnancy eugenic health examinations at Huzhou Maternity and Child Health Care Hospital as the research subjects. A total of 100 women of childbearing age who received pre-pregnancy eugenic health examination and education from January to December 2024 were assigned to the observation group. Using 1:1 baseline matching, 100 women of childbearing age who received “free pre pregnancy eugenics health check ups” from January to December 2023 were selected as the control group. Scores of the Eugenics Health Knowledge-Belief-Behavior questionnaire, Hamilton Anxiety Scale (HAMA), and Health Promoting Lifestyle Profile-II (HPLP-II) were compared between groups before intervention (pre-pregnancy) and after intervention (early pregnancy). The incidence of adverse pregnancy outcomes and neonatal defects was also compared.
RESULTS
Before intervention, there were no statistically significant differences between the two groups in knowledge-belief-behavior, HAMA, or HPLP-II scores (P > 0.05). After intervention, the observation group showed higher knowledge-belief-behavior scores, lower HAMA scores, and higher HPLP-II scores compared with the control group (P < 0.05). The incidence of adverse pregnancy outcomes (premature birth, low birth weight, and macrosomia) and neonatal birth defects was significantly lower in the observation group than in the control group (P < 0.05).
CONCLUSION
Pre-pregnancy eugenic health examination and education improves knowledge-belief-behavior, alleviates anxiety, and improve risk-aversion behavior in women of childbearing age, thereby contributing to improved pregnancy outcomes and reduced neonatal birth defects.
Core Tip: Pre-pregnancy eugenic health examination alone may be insufficient to reduce psychology burden or birth defects in women of childbearing age. Therefore, integrating targeted health education enhances knowledge-belief-behavior, promotes risk-aversion behaviors, reduces anxiety, and contributes to improved pregnancy outcomes and reduced neonatal birth defects.
