Guo YL, Duan JF, Li JP. Cognitive behavioral intervention for depressive disorders in patients after cervical cancer surgery. World J Psychiatry 2026; 16(11): 123042 [DOI: 10.5498/wjp.123042]
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Guo YL, Duan JF, Li JP. Cognitive behavioral intervention for depressive disorders in patients after cervical cancer surgery. World J Psychiatry 2026; 16(11): 123042 [DOI: 10.5498/wjp.123042]
World J Psychiatry. Nov 19, 2026; 16(11): 123042 Published online Nov 19, 2026. doi: 10.5498/wjp.123042
Cognitive behavioral intervention for depressive disorders in patients after cervical cancer surgery
Ya-Li Guo, Jun-Fang Duan, Jing-Ping Li
Ya-Li Guo, Jing-Ping Li, Department of Gynecology, Shanxi Provincial People’s Hospital, Taiyuan 030012, Shanxi Province, China
Jun-Fang Duan, Department of Outpatient, Taiyuan Mental Hospital, Taiyuan 030012, Shanxi Province, China
Author contributions: Guo YL participated in the research design, data collection, literature review, data entry and organization; Guo YL and Duan JF participated in the statistical analysis and result interpretation; Guo YL and Li JP participated in the research guidance, statistical analysis, paper writing and paper revision. All authors critically reviewed and provided final approval of the manuscript, all authors were responsible for the decision to submit the manuscript for publication.
AI contribution statement: No AI tools were used in the composition, editing or figure creation of this manuscript. The entire manuscript is fully original work of all authors.
Institutional review board statement: The study was approved by the Ethics Committee of Shanxi Provincial People’s Hospital (approval No. 2026327).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The original anonymous dataset is available on request from the corresponding author at syfk415@126.com.
Received: June 10, 2026 Revised: July 3, 2026 Accepted: July 27, 2026 Published online: November 19, 2026 Processing time: 140 Days and 22.2 Hours
Abstract
BACKGROUND
Cervical cancer is a common cancer type affecting women. Currently, surgical treatment is the primary clinical approach for cervical cancer. However, owing to various factors, patients are prone to developing depressive symptoms after surgery, which adversely affects their disease prognosis and quality of life. Therefore, the implementation of effective psychological interventions for patients in the postoperative period is critical.
AIM
To investigate the effects of cognitive behavioral intervention (CBI) on depression in post-cervical cancer surgery patients.
METHODS
In this retrospective study, clinical and follow-up data were collected from patients undergoing radical cervical cancer surgery at Shanxi Provincial People’s Hospital (2023-2025); 185 participants were enrolled via consecutive retrospective sampling and divided into observation and control groups. The observation group received postoperative 8-week standardized CBI once weekly, delivered by professionally trained nurses to alleviate postoperative negative emotions. Propensity score matching was used to balance baseline confounders. Depression incidence, symptom scores, remission rate, quality of life, and treatment compliance were compared between the groups. Multivariate logistic regression identified independent factors for postoperative depression.
RESULTS
A total of 185 patients were enrolled; the observation and control groups each comprised 84 patients after propensity score matching. Baseline data were well-balanced across the two groups after matching. At 6 months postoperatively, the observation group exhibited markedly lower depression symptom scores and a lower incidence of depressive disorders compared with the control group, while the depression symptom remission rate, quality of life score, and treatment compliance were significantly higher (6.5 ± 1.3 vs 8.9 ± 1.9, P < 0.001; 20.2% vs 41.7%, P < 0.01; 51.8% vs 4.8%, P < 0.001; 18.0 ± 3.6 vs 15.8 ± 3.4, P < 0.001; 72.6% vs 44.0%, P < 0.001). Multivariate regression analysis showed that CBI was an independent protective factor against depressive disorders in patients after cervical cancer surgery, whereas older age and postoperative chemoradiotherapy were independent risk factors (all P < 0.05).
CONCLUSION
Standardized cognitive behavioral therapy lowers depression risk, relieves symptoms, and improves remission rate for cervical cancer postoperative patients. Thus, this intervention is worthy of clinical promotion.
Core Tip: This study investigated the impact of cognitive behavioral intervention (CBI) on depressive symptom severity, remission rate, and incidence of depressive disorders among patients following cervical cancer surgery. After the CBI, the observation group exhibited significantly lower depression symptom scores and incidence of depressive disorders than the control group (P < 0.05), as well as better depression symptom remission rate, quality of life score, and treatment compliance (P < 0.05). These results support the effectiveness of CBI in patients after cervical cancer surgery.
