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Observational Study
Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Psychiatry. Nov 19, 2026; 16(11): 122321
Published online Nov 19, 2026. doi: 10.5498/wjp.122321
Depression and anxiety symptoms among operating room nurses: Prevalence and correlations with occupational environmental factors
Xi-Qian Gu, Ni-Na Zhong, Kun-Xian Zhang, Zhi Cheng, Yang Xiang, Xiao-Min Ding, Jing-Ying Yang, Yi-Yun Zhang, Di Zhang
Xi-Qian Gu, Ni-Na Zhong, Kun-Xian Zhang, Zhi Cheng, Yang Xiang, Jing-Ying Yang, Yi-Yun Zhang, Di Zhang, Department of Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei Province, China
Xiao-Min Ding, Department of Neuropsychology, Zhongnan Hospital of Wuhan University, Wuhan 430071, Hubei Province, China
Co-first authors: Xi-Qian Gu and Ni-Na Zhong.
Co-corresponding authors: Yi-Yun Zhang and Di Zhang.
Author contributions: Gu XQ and Zhong NN contributed to conceptualization, data curation, formal analysis, investigation, methodology, writing original draft; Zhang KX, Cheng Z, Xiang Y, Ding XM and Yang JY contributed to data curation, investigation, validation; Zhang YY and Zhang D contributed to conceptualization, project administration, resources, supervision, writing review and editing; Gu XQ and Zhong NN are co-first authors; Zhang YY and Zhang D are co-corresponding authors.
AI contribution statement: This article is independently written by the author without any assistance from artificial intelligence tools throughout the process.
Institutional review board statement: The study was reviewed and approved by Institutional Review Board of Zhongnan Hospital of Wuhan University (No. 2026100K).
Informed consent statement: All study participants provided written informed consent before study enrollment.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
STROBE statement: The authors have read the STROBE Statement—a checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-a checklist of items.
Data sharing statement: Owing to ethical constraints involving human participants, raw data cannot be shared publicly. De-identified datasets are available from the corresponding author (evianzhang0128@126.com) on request.
Corresponding author: Yi-Yun Zhang, MD, Doctor, Department of Surgery, Zhongnan Hospital of Wuhan University, No. 169 Donghu Road, Wuchang District, Wuhan 430071, Hubei Province, China. evianzhang0128@126.com
Received: May 15, 2026
Revised: June 23, 2026
Accepted: July 17, 2026
Published online: November 19, 2026
Processing time: 166 Days and 22.8 Hours
Abstract
BACKGROUND

Operating room nurses, working in a persistently high-pressure and demanding work environment, are at high risk of psychological distress. Their mental health status not only affects personal well-being but is also closely related to patient safety and medical quality.

AIM

To study depression and anxiety symptoms in operating room nurses and explored their association with multidimensional occupational environmental factors.

METHODS

This cross-sectional survey recruited operating room nurses between October 2024 and October 2025. Participants completed general information questionnaires and standardized scales to collect data on demographics, occupational characteristics, anxiety and depression symptoms, and work environments. Pearson correlation and linear regression analyses were used to explore the relationship between depression, anxiety symptoms, and occupational environmental factors.

RESULTS

We surveyed 151 nurses. The prevalence of anxiety symptoms was 56.95% (76.75% mild, 18.60% moderate, 4.65% severe). The prevalence of depressive symptoms was 62.91% (56.84% mild, 34.74% moderate, 8.42% severe). Anxiety and depression varied significantly according to demographic and occupational factors. Higher rates were found among nurses aged 26-36 years, those with 6-10 years of operating room tenure, Nurse-in-Charge, and scrub nurses. Depression scores and prevalence were significantly higher among female nurses (all P < 0.05). Correlation analysis indicated significant negative associations between occupational environment and both anxiety and depressive symptoms (P < 0.05). Occupational environmental factors independently explained an additional 28.6% of the variance in anxiety symptoms and 7.6% of the variance in depression symptoms.

CONCLUSION

Operating room nurses showed high rates of anxiety and depression, which were negatively correlated with the occupational environment. Therefore, targeted mental-health interventions are required in this population.

Keywords: Operating room nurses; Depression; Anxiety; Mental health; Occupational environment; Status survey; Correlation analysis; Influencing factors

Core Tip: We surveyed 151 operating room nurses. The prevalences of anxiety and depressive symptoms were 56.95% and 62.91%, respectively, with most cases being mild-to-moderate. Symptoms were more common among nurses aged 26-36 years, those with 6-10 years of experience, Nurse-in-Charge, and scrub nurses. Female nurses had significantly higher levels of depression than male nurses. The occupational environment was negatively correlated with anxiety and depression and was an independent influencing factor. Therefore, targeted mental-health interventions should be implemented.

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