Published online Oct 19, 2026. doi: 10.5498/wjp.121800
Revised: May 12, 2026
Accepted: July 10, 2026
Published online: October 19, 2026
Processing time: 191 Days and 7.6 Hours
University students in Pakistan are silently experiencing psychological distress due to economic instability, academic pressure, and a lack of mental health services. In this context, physical activity (PA) has been proposed as an evidence-based, cost-effective, non-stigmatizing, and accessible adjunctive behavioral intervention. However, our understanding of its mechanism of action within Pakistan’s unique socio-cultural context remains limited. Factors such as gender norms, religious beliefs, family expectations, and institutional constraints may significantly shape how PA influences mental health outcomes among Pakistani students. Without context-specific research, the potential of PA as a feasible mental health strategy cannot be fully realized or appropriately implemented.
To examine the association of PA with depression, anxiety, and stress and to test a comprehensive theoretical model in which self-efficacy, sleep quality, and social support serve as parallel mediators in the relationship between PA and psychological well-being.
A cross-sectional survey was conducted with 708 students from six public and private universities in three provinces of Pakistan using multistage cluster sampling. The participants completed validated scales, including the Depression Anxiety Stress Scale, International Physical Activity Questionnaire, General Self-Efficacy Scale, Multidimensional Perceived Social Support Scale, and Pittsburgh Sleep Quality Index. Descriptive statistics, Pearson’s correlation coefficient, and structural equation modeling (SEM) were used to analyze the data.
SEM analysis shows that the model fits well (comparative fit index = 0.95, root mean square error of approximation = 0.04). PA has a significant direct negative impact on psychological distress (β = -0.28, P < 0.001). The indirect effects generated through the medium are also significant: Self-efficacy (β = -0.16, P < 0.001), sleep quality (β = -0.12, P < 0.001), and social support (β = -0.09, P = 0.002), accounting for a large part of the total impact.
PA may alleviate psychological distress by improving self-efficacy, sleep quality, and social support. These findings support the inclusion of structured PA, sleep hygiene, and supportive campuses in Pakistan’s student mental health strategy.
Core Tip: This study had two main goals. First, it aimed to directly investigate how physical activity (PA) affects levels of depression, anxiety, and stress. Second, it sought to test a detailed theoretical model to understand how PA leads to better psychological well-being.