Miao G, Guan HY, Wang XJ. Post-stroke depression in patients with chronic stroke. World J Psychiatry 2026; 16(1): 114202 [DOI: 10.5498/wjp.v16.i1.114202]
Corresponding Author of This Article
Xue-Jian Wang, MD, PhD, Department of Neurosurgery, Affiliated Hospital 2 of Nantong University, No. 702 East, No. 666 Shengli Road, Chongchuan District, Nantong 226000, Jiangsu Province, China. 6841441@163.com
Research Domain of This Article
Psychiatry
Article-Type of This Article
Letter to the Editor
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Psychiatry. Jan 19, 2026; 16(1): 114202 Published online Jan 19, 2026. doi: 10.5498/wjp.v16.i1.114202
Post-stroke depression in patients with chronic stroke
Guo Miao, Hai-Yang Guan, Xue-Jian Wang
Guo Miao, Clinical Medical School, Southeast University, Nanjing 210000, Jiangsu Province, China
Guo Miao, Xue-Jian Wang, Department of Neurosurgery, Nantong Hospital Affiliated to Southeast University, Nantong 226000, Jiangsu Province, China
Hai-Yang Guan, Department of Emergency Medicine, Nantong Hospital Affiliated to Southeast University, Nantong 221000, Jiangsu Province, China
Xue-Jian Wang, Department of Neurosurgery, Affiliated Hospital 2 of Nantong University, Nantong 226000, Jiangsu Province, China
Author contributions: Miao G writing-review and editing; Wang XJ conceptualization, writing-original draft, writing-review and editing; Guan HY review and editing.
Supported by Science and Technology Program of Nantong City, No. Key003 and No. JCZ2022040; Nantong Young Medical Expert, No. 46; Science and Technology Program of Nantong Health Committee, No. MA2019003, No. MA2021017, and No. MSZ2024038; Kangda College of Nanjing Medical University, No. KD2021JYYJYB025, No. KD2022KYJJZD022, and No. KD2024KYJJZD289; and Nantong Municipal Health Commission Project, No. MSZ2023020.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xue-Jian Wang, MD, PhD, Department of Neurosurgery, Affiliated Hospital 2 of Nantong University, No. 702 East, No. 666 Shengli Road, Chongchuan District, Nantong 226000, Jiangsu Province, China. 6841441@163.com
Received: September 15, 2025 Revised: October 1, 2025 Accepted: November 3, 2025 Published online: January 19, 2026 Processing time: 108 Days and 17 Hours
Abstract
Stroke is the second leading cause of death worldwide and a major cause of disability among adults. With the advancement of medical technology, the survival period of stroke patients has been significantly prolonged, but the neuropsychiatric sequelae in the chronic stage have become increasingly prominent. Post-stroke depression is one of the very important manifestations. This article conducts a further discussion on this issue.
Core Tip: Stroke is one of the major diseases affecting global health at present. With the improvement of treatment levels, the mortality and disability rates have improved compared with before. However, various diseases after stroke still affect patients' long-term lives, such as post-stroke depression (PSD). This article is in response to the paper by Han et al. We will further discuss PSD in the hope of enhancing everyone's understanding.
