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Copyright ©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Psychiatry. Jan 19, 2026; 16(1): 109725
Published online Jan 19, 2026. doi: 10.5498/wjp.v16.i1.109725
Influence of cognitive behavioral therapy-based psychological interventions on psychological well-being and quality of life among laryngeal carcinoma patients
Hong-Zhu Tao, You-Min Deng, Shu-Feng Xia, Yan Feng
Hong-Zhu Tao, Department of Head and Neck Oncology, Chongqing University Cancer Hospital, Chongqing Cancer Institute, Chongqing Cancer Hospital, Chongqing 400030, China
You-Min Deng, Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing Cancer Institute, Chongqing Cancer Hospital, Chongqing 400030, China
Shu-Feng Xia, Yan Feng, Department of Integrated, Chongqing University Cancer Hospital, Chongqing Cancer Institute, Chongqing Cancer Hospital, Chongqing 400030, China
Co-first authors: Hong-Zhu Tao and You-Min Deng.
Co-corresponding authors: Shu-Feng Xia and Yan Feng.
Author contributions: Tao HZ and Deng YM contributed to the conception and design; Tao HZ, Deng YM, Xia SF and Feng Y contributed to the analysis and interpretation of data; Tao HZ and Deng YM contributed to the writing, review, and/or revision of the manuscript; Tao HZ and Deng YM contributed equally to this manuscript and are co-first authors; Xia SF and Feng Y contributed equally to this manuscript and are co-corresponding authors. All authors contributed to the acquisition of data, acquired and managed patients, and final approved the manuscript.
Institutional review board statement: This study was approved by the Ethic Committee of Chongqing University Cancer Hospital.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shu-Feng Xia, Department of Integrated, Chongqing University Cancer Hospital, Chongqing Cancer Institute, Chongqing Cancer Hospital, No. 181 Hanyu Road, Shapingba District, Chongqing 400030, China. 13983823428@163.com
Received: August 19, 2025
Revised: September 18, 2025
Accepted: November 7, 2025
Published online: January 19, 2026
Processing time: 133 Days and 18.9 Hours
Abstract
BACKGROUND

Approximately 30% of patients with head and neck cancer experience adverse effects caused by anxiety and depression. Considering the high prevalence, implementing customized interventions to ease adverse emotional states is imperative.

AIM

To evaluate the efficacy of cognitive behavioral therapy (CBT)-based psychological interventions in improving the psychological well-being and quality of life (QoL) of patients with laryngeal carcinoma.

METHODS

This study enrolled 120 patients admitted from February 2022 to February 2024. The control group, comprising 50 participants, received standard supportive psychological care, while the research group, consisting 70 participants, underwent CBT-based interventions. Several clinical outcomes were systematically assessed that included postoperative recovery metrics (duration of tracheostomy and nasogastric tube dependence and length of hospitalization), psychological status (Self-Rating Anxiety Scale and Self-Rating Depression Scale), nutritional markers (serum albumin and hemoglobin levels), sleep quality (Self-Rating Scale of Sleep and Athens Insomnia Scale), and QoL (Functional Assessment of Cancer Therapy-Head and Neck).

RESULTS

The results demonstrated that the research group experienced superior outcomes, with significantly reduced durations of tracheostomy and nasogastric tube dependence, as well as shorter hospital stays, compared with the control group. Additionally, the research group exhibited markedly lower post-intervention Self-Rating Anxiety Scale, Self-Rating Depression Scale, Self-Rating Scale of Sleep, and Athens Insomnia Scale scores, along with minimal but higher change in serum albumin and hemoglobin levels compared with the control group. All five domains of Functional Assessment of Cancer Therapy-Head and Neck showed notable improvements in the research group, exceeding those observed in the control group.

CONCLUSION

CBT-based psychological support positively affects the mental well-being and QoL of patients with laryngeal carcinoma, highlighting its potential for broader clinical application.

Keywords: Laryngeal carcinoma; Cognitive behavioral therapy; Psychological intervention; Mental state; Quality of life

Core Tip: This study primarily aimed to evaluate the efficacy of cognitive behavioral therapy-based psychological interventions in influencing the mental state and quality of life of 120 patients with laryngeal carcinoma. Through quantitative assessments across multiple domains (e.g., postoperative recovery, mental/nutritional status, sleep/life quality), we confirmed that cognitive behavioral therapy-based psychological interventions provide greater clinical benefits compared with conventional supportive psychological care.