Nagamine T. Nutritional psychiatry for hypertensive older adults. World J Psychiatry 2025; 15(6): 106262 [DOI: 10.5498/wjp.v15.i6.106262]
Corresponding Author of This Article
Takahiko Nagamine, MD, PhD, Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, 4-13-18 Jiyugaoka, Hofu 7470066, Yamaguchi, Japan. anagamine@yahoo.co.jp
Research Domain of This Article
Psychiatry
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Psychiatry. Jun 19, 2025; 15(6): 106262 Published online Jun 19, 2025. doi: 10.5498/wjp.v15.i6.106262
Nutritional psychiatry for hypertensive older adults
Takahiko Nagamine
Takahiko Nagamine, Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, Hofu 7470066, Yamaguchi, Japan
Author contributions: Nagamine T designed and conceived the study, collected the data, analyzed and interpreted the results, drafted the manuscript, and has read and agreed to the published version of the manuscript.
Conflict-of-interest statement: All authors have no conflicts of interest to declare.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Takahiko Nagamine, MD, PhD, Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, 4-13-18 Jiyugaoka, Hofu 7470066, Yamaguchi, Japan. anagamine@yahoo.co.jp
Received: February 21, 2025 Revised: March 28, 2025 Accepted: April 3, 2025 Published online: June 19, 2025 Processing time: 98 Days and 8.5 Hours
Abstract
Hypertension, a prevalent condition among older adults, has been identified as a risk factor for cognitive decline. Nutritional status is a pivotal factor in preserving cognitive function in hypertensive older adults. Nutritional psychiatry underscores the significance of anti-inflammatory diets in promoting mental and cognitive health. This article examined the mechanisms by which body mass index, serum hemoglobin, serum albumin, and alkaline phosphatase levels predict cognitive function in hypertensive older adults. Nutrition emerges as a modifiable factor that can be targeted to maintain cognitive function in these patients.
Core Tip: In hypertensive older adults, body mass index (BMI), serum hemoglobin, and serum albumin levels have been identified as independent protective factors for cognitive function. Conversely, alkaline phosphatase (ALP) has been associated with cognitive decline. BMI, hemoglobin, and albumin are commonly used as indicators of nutritional status, and poor nutritional status has been linked to poorer cognitive function. While ALP itself does not directly impact cognitive function, it serves as a marker of overall status and can predict cognitive decline.
