Effects of suggestion therapy on mood and sleep quality in middle-aged women with depression

doi:10.5498/wjp.v15.i3.100009

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Psychiatry. Mar 19, 2025; 15(3): 100009
Published online Mar 19, 2025. doi: 10.5498/wjp.v15.i3.100009

Effects of suggestion therapy on mood and sleep quality in middle-aged women with depression

Yuan Jiang, Ke-Ke Xia, Zhi-Yuan Lin

Yuan Jiang, Ke-Ke Xia, Department of Psychiatry, The Seventh People’s Hospital of Wenzhou, Wenzhou 325000, Zhejiang Province, China

Zhi-Yuan Lin, General Psychiatry, The Seventh People’s Hospital of Wenzhou, Wenzhou 325000, Zhejiang Province, China

Author contributions: Jiang Y performed the primary literature and data extraction; Xia KK analyzed the data and wrote the manuscript; Lin ZY was responsible for revising the manuscript for important intellectual content; and all authors read and approved the final version.

Institutional review board statement: The study was reviewed and approved by the Seventh People’s Hospital of Wenzhou.

Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Data sharing statement: The datasets used and/or analysed during the current study available from the corresponding author on reasonable request.

Corresponding author: Zhi-Yuan Lin, General Psychiatry, The Seventh People’s Hospital of Wenzhou, No. 552 Xishan East Road, Ouhai District, Wenzhou 325000, Zhejiang Province, China. linzhy1234@163.com

Received: October 31, 2024
Revised: December 7, 2024
Accepted: January 6, 2025
Published online: March 19, 2025
Processing time: 117 Days and 20.3 Hours

Abstract

BACKGROUND

Depression is one of the most common mental disorders, with high rates of disability, particularly among women.

AIM

To explore the effects of suggestion therapy on anxiety, mood, and sleep-quality in middle-aged women with depression treated with escitalopram.

METHODS

Overall, 102 female patients with depression aged 35-49 years were divided into control and experimental groups. The control group received oral escitalopram therapy, starting at a dose of 5 mg/day, which was gradually increased to 10-20 mg/day after 1 week for a total of 8 weeks. The experimental group received the suggested therapy based on the control group. The Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS), Profile of Mood States-Short Form, and Pittsburgh Sleep Quality Index (PSQI) were used to assess depression, anxiety, mood status, and sleep quality.

RESULTS

Before treatment, there were no significant differences in the SDS, SAS, Profile of Mood States, and PSQI scores between the two groups (P > 0.05). After treatment, compared to the control group and baseline, the SDS, SAS, tension-anxiety, depression-dejection, and confusion-bewilderment scores in the experimental group significantly decreased (P < 0.05), whereas sleep efficiency, sleep disturbance, hypnotics, and PSQI scores significantly increased (P < 0.05).

CONCLUSION

Suggestion therapy combined with escitalopram treatment can reduce the severity of depression and anxiety, change mood status, and improve sleep quality in middle-aged women with depression.

Keywords: Suggestion therapy; Escitalopram; Middle-aged women depression; Mood state; Sleep quality

Core Tip: Depression is one of the most common mental disorders associated with high rates of disability, especially among women. This study aimed to determine the effect of suggestion therapy combined with escitalopram on depression in middle-aged women and to explore its effects on their mental state and sleep quality. The results of the clinical experiments can provide a scientific basis for improving the treatment of depression in middle-aged women.