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World J Psychiatry. Dec 19, 2025; 15(12): 111516
Published online Dec 19, 2025. doi: 10.5498/wjp.v15.i12.111516
Acute poisoning and psychological trauma: Bridging emergency care to long-term mental health rehabilitation
Cai-Xia Lin, Xia-Rong Liu, Kun-Bin Lin
Cai-Xia Lin, Department of Nursing, The First Hospital Affiliated to Fujian Medical University, Quanzhou 362000, Fujian Province, China
Xia-Rong Liu, Kun-Bin Lin, Department of Emergency, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou 362000, Fujian Province, China
Author contributions: Lin CX responsible for experimental design and paper writing; Liu XR and Liu KB completed data collection and analysis; Liu XR provided theoretical guidance and result verification; Lin CX and Liu XR supervised the project and revised the manuscript.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Cai-Xia Lin, Department of Nursing, The First Hospital Affiliated to Fujian Medical University, No. 1028 Anji South Road, Fengze District, Quanzhou 362000, Fujian Province, China. lcx22882728@126.com
Received: July 1, 2025
Revised: July 29, 2025
Accepted: September 17, 2025
Published online: December 19, 2025
Processing time: 149 Days and 1.1 Hours
Abstract

This review addresses the critical intersection between acute poisoning and the associated psychological trauma, highlighting the need to bridge the gap between emergency care and long-term mental health rehabilitation. The global incidence of acute poisoning varies, showing different demographic patterns in psychological trauma post-poisoning, with suicide attempts accounting for approximately 76% of cases in some cohorts. Additionally, an estimated 385 million unintentional pesticide poisonings occur annually worldwide. A comprehensive understanding of the biological and neurobiological mechanisms involved—along with accurate diagnostic strategies and treatment methods—is essential. Multidisciplinary and integrated care approaches associated with a reduction in all-cause mortality (odds ratio: 0.52) and significant symptom burden relief, along with technological and therapeutic innovations, are essential for improving patient outcomes. Finally, this review outlines policy and research recommendations to enhance integrated care systems for the better management of acute poisoning and its associated psychological trauma.

Keywords: Acute poisoning; Psychological trauma; Emergency care; Long-term rehabilitation; Integrated care

Core Tip: This review examines acute poisoning and linked psychological trauma, stressing the integration of emergency care with long-term mental health rehabilitation. It explores epidemiology, pathophysiology, diagnostics, treatments, and future research directions, aiming to enhance patient outcomes through multidisciplinary and innovative approaches.