Neural correlates of attentional switching dysfunction in major depressive disorder: Evidence from an event-related potential study with a dual-task paradigm
Ya-Wen Wu, Xin-Yu Wang, Yi-Fan Sun, Luo-An Wu, Wei Li, Yu Li, Xue-Zheng Gao, Xiao-Hong Liu, Zhen-He Zhou, Hong-Liang Zhou
Ya-Wen Wu, Xin-Yu Wang, Yi-Fan Sun, Xue-Zheng Gao, Xiao-Hong Liu, Zhen-He Zhou, Department of Psychiatry, The Affiliated Mental Health Center of Jiangnan University, Wuxi 214151, Jiangsu Province, China
Luo-An Wu, Wei Li, Yu Li, Department of Psychiatry, The Yixing Fifth People’s Hospital, Yixing 214200, Jiangsu Province, China
Hong-Liang Zhou, Department of Psychology, The Affiliated Hospital of Jiangnan University, Wuxi 214151, Jiangsu Province, China
Co-first authors: Ya-Wen Wu and Xin-Yu Wang.
Co-corresponding authors: Zhen-He Zhou and Hong-Liang Zhou.
Author contributions: Zhou ZH and Zhou HL designed the study and contributed equally as co-corresponding authors; Wu YW, Wang XY, Sun YF, Wu LA, Li W, Li Y, Gao XZ, and Liu XH recruited participants and collected the data; Wu YW and Wang XY contributed equally as co-first authors; Wu YW, Wang XY, Zhou ZH and Zhou HL analyzed data and drafted the manuscript; and all the authors contributed to the interpretation of the results, manuscript revision, and approved the final version of the manuscript.
Supported by Wuxi Taihu Talent Project, No. WXTTP 2021; and the General Scientific Research Program of Wuxi Municipal Health Commission, No. M202447.
Institutional review board statement: This study was approved by the Medical Ethics Committee of the Wuxi Mental Health Center, No. WXMHCIRB2025 LLky018.
Informed consent statement: All participants enrolled in this study provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: Data used in this study can be made available from the corresponding author upon request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Zhen-He Zhou, PhD, Chief Physician, Full Professor, Department of Psychiatry, The Affiliated Mental Health Center of Jiangnan University, No. 156 Qianrong Road, Wuxi 214151, Jiangsu Province, China.
zhouzh@njmu.edu.cn
Received: July 2, 2025
Revised: August 12, 2025
Accepted: October 11, 2025
Published online: December 19, 2025
Processing time: 149 Days and 0.9 Hours
